Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28928751
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28928751
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Front+Immunol
2017 ; 8
(ä): 1095
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
"Multi-Omics" Analyses of the Development and Function of Natural Killer Cells
#MMPMID28928751
Zhou Y
; Xu X
; Tian Z
; Wei H
Front Immunol
2017[]; 8
(ä): 1095
PMID28928751
show ga
For over four decades, our understanding of natural killer (NK) cells has evolved
from the original description of cluster of differentiation (CD)56(+)CD3(-) to
establishing NK cells as an important subset of innate lymphocytes in the host's
surveillance against viral infections and malignancy. The progress of research on
the fundamental properties and therapeutic prospects for translational medicine
using NK cells excites immunologists and clinicians. Over the past decade,
numerous advances in "-omics"-scale methods and new technological approaches have
addressed many essential questions in the biology of NK cells. We now have
further understanding of the overall molecular mechanisms of action that
determine the development, function, plasticity, diversity, and immune reactivity
of NK cells. These findings are summarized here, and our view on how to study NK
cells using "multi-omics" is highlighted. We also describe "-omics" analyses of
the relationships between NK cells and viral infection, tumorigenesis, and
autoimmune diseases. Ultimately, a deeper and more comprehensive understanding of
NK cells in multiple conditions will provide more effective strategies to
manipulate NK cells for the treatment of human disease.