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10.1038/ki.2014.272

http://scihub22266oqcxt.onion/10.1038/ki.2014.272
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suck abstract from ncbi


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pmid25140912
      Kidney+Int 2015 ; 87 (2 ): 442-51
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  • A systematic review and meta-analysis indicates underreporting of renal dysfunction following endovascular aneurysm repair #MMPMID25140912
  • Karthikesalingam A ; Bahia SS ; Patel SR ; Azhar B ; Jackson D ; Cresswell L ; Hinchliffe RJ ; Holt PJ ; Thompson MM
  • Kidney Int 2015[Feb]; 87 (2 ): 442-51 PMID25140912 show ga
  • Deterioration in renal function has been described after endovascular repair of abdominal aortic aneurysms (EVRs). The etiology is multifactorial and represents an important therapeutic target. A need exists to quantitatively summarize incidence and severity of renal dysfunction after EVR to allow better-informed attempts to preserve renal function and improve life expectancy. Here a systematic search was performed using Medline and Embase for renal function after EVR applying PRISMA statements. Univariate and multivariate random-effects meta-analyses were performed to estimate pooled postoperative changes in serum creatinine and creatinine clearance at four time points after EVR. Clinically relevant deterioration in renal function was also estimated at 1 year or more after EVR. Pooled probability of clinically relevant deterioration in renal function at 1 year or more was 18% (95% confidence interval of 14-23%, I2 of 82.5%). Serum creatinine increased after EVR by 0.05?mg/dl at 30 days/1 month, 0.09?mg/dl at 1 month to 1 year, and 0.11?mg/dl at 1 year or more (all significant). Creatinine clearance decreased after EVR by 5.65 ml/min at 1 month-1 year and by 6.58?ml/min at 1 year or more (both significant). Thus, renal dysfunction after EVR is common and merits attention.
  • |Aortic Aneurysm, Abdominal/*surgery [MESH]
  • |Creatinine/blood [MESH]
  • |Endovascular Procedures/*adverse effects [MESH]
  • |Humans [MESH]
  • |Kidney/*physiopathology [MESH]
  • |Postoperative Complications/etiology/physiopathology [MESH]
  • |Renal Insufficiency/etiology/physiopathology [MESH]


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