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2017 ; 4
(ä): 69
Nephropedia Template TP
gab.com Text
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Into the eyes of bone marrow-derived mesenchymal stem cells therapy for
myocardial infarction and other diseases
#MMPMID28920062
Li JR
; Qu TT
Stem Cell Investig
2017[]; 4
(ä): 69
PMID28920062
show ga
Applications of bone marrow-derived mesenchymal stem cells (BM-MSCs) have been
documented for diseases occur in the sports system, the central nervous system,
the cardiovascular system etc. However, poor viability of donor stem cells after
transplantation limits their therapeutic efficiency. Although the autophagy
theory has been reported, the underlying mechanisms are still poorly understood.
Isolation and culture methods of mesenchymal stem cells are currently concentrate
on four ways. Overall, BM-MSCs have both important research significance and
clinical application value in cell replacement therapy, gene therapy and
reconstruction of tissues as well as organs especially for myocardial infarction
(MI). In this article, we review the biological characteristics of BM-MSCs and
its research progress especially in MI.