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10.1136/bcr-2017-221032 http://scihub22266oqcxt.onion/10.1136/bcr-2017-221032 C5589033!5589033 !28882938     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28882938 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMJ+Case+Rep 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=28882938 |t=2017. Imatinib dramatically alleviates pulmonary tumour thrombotic microangiopathy induced by gastric cancer |pdf=|usr=}}{{28882938 }} gab.com Text Imatinib dramatically alleviates pulmonary tumour thrombotic microangiopathy induced by gastric cancer JO: BMJ Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=28882938 #FOAvip Pulmonary tumour thrombotic microangiopathy (PTTM) is a rare complication of cancer, which can be lethal due to progressive pulmonary hypertension (PH). Several case reports have demonstrated that imatinib, a platelet-derived growth factor receptor-tyrosine kinase inhibitor, can improve severe PH in patients with PTTM.We describe the case of a 56-year-old woman. Her mean pulmonary arterial pressure (mPAP) was 47?mm Hg, and her dyspnoea worsened rapidly over several days. Although pulmonary embolism was not observed on CT, enlargement of the para-aortic lymph nodes was detected. Gastro-oesophageal endoscopy revealed signet-ring cell carcinoma. We diagnosed her as having PTTM based on her clinical course, and started treatment with imatinib. Five days after its administration, her mPAP decreased dramatically. She was discharged and lived without symptoms of PH until her death due to systemic metastasis of carcinoma. In some cases of PTTM, imatinib may be an effective therapeutic option for PH. Twit Text FOAVip Imatinib dramatically alleviates pulmonary tumour thrombotic microangiopathy induced by gastric cancer ????BMJ Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=28882938 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28882938 #FOAvip English Wikipedia <ref>{{Cite pmid|28882938 }}</ref> Imatinib dramatically alleviates pulmonary tumour thrombotic microangiopathy induced by gastric cancer #MMPMID28882938 Kubota K ; Shinozaki T ; Imai Y ; Kario K BMJ Case Rep 2017[Sep]; 2017 (ä): ä PMID28882938 show ga Pulmonary tumour thrombotic microangiopathy (PTTM) is a rare complication of cancer, which can be lethal due to progressive pulmonary hypertension (PH). Several case reports have demonstrated that imatinib, a platelet-derived growth factor receptor-tyrosine kinase inhibitor, can improve severe PH in patients with PTTM.We describe the case of a 56-year-old woman. Her mean pulmonary arterial pressure (mPAP) was 47?mm Hg, and her dyspnoea worsened rapidly over several days. Although pulmonary embolism was not observed on CT, enlargement of the para-aortic lymph nodes was detected. Gastro-oesophageal endoscopy revealed signet-ring cell carcinoma. We diagnosed her as having PTTM based on her clinical course, and started treatment with imatinib. Five days after its administration, her mPAP decreased dramatically. She was discharged and lived without symptoms of PH until her death due to systemic metastasis of carcinoma. In some cases of PTTM, imatinib may be an effective therapeutic option for PH. |Carcinoma, Signet Ring Cell/diagnostic imaging/pathology/*secondary [MESH] |Fatal Outcome [MESH] |Female [MESH] |Humans [MESH] |Hypertension, Pulmonary/drug therapy [MESH] |Imatinib Mesylate/administration & dosage/*therapeutic use [MESH] |Lung Neoplasms/pathology/*secondary [MESH] |Middle Aged [MESH] |Protein Kinase Inhibitors/therapeutic use [MESH] |Rare Diseases [MESH] |Receptors, Platelet-Derived Growth Factor/*antagonists & inhibitors [MESH] |Stomach Neoplasms/*complications/pathology [MESH] |Thrombotic Microangiopathies/*complications/*drug therapy [MESH]Imatinib dramatically alleviates pulmonary tumour thrombotic microangi(epmc).pdf DeepDyve Pubget Overpricing