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10.1136/bmjopen-2017-016490 http://scihub22266oqcxt.onion/10.1136/bmjopen-2017-016490 C5588992!5588992!28864484     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMJ+Open 2017 ; 7 (8): ä Nephropedia Template TP {{tp|p=28864484|t=2017. Lifetime risks of kidney donation: a medical decision analysis |pdf=|usr=}}{{28864484}} gab.com Text Lifetime risks of kidney donation: a medical decision analysis JO: BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=28864484 #FOAvip Objective: This study estimated the potential loss of life and the lifetime cumulative risk of end-stage renal disease (ESRD) from live kidney donation. Design: Markov medical decision analysis. Setting: USA. Participants: 40-year-old live kidney donors of both sexes and black/white race. Intervention: Live donor nephrectomy. Main outcome and measures: Potential remaining life years lost, quality-adjusted life years (QALYs) lost and added lifetime cumulative risk of ESRD from donation. Results: Overall 0.532?0.884 remaining life years were lost from donating a kidney. This was equivalent to 1.20%?2.34% of remaining life years (or 0.76%?1.51% remaining QALYs). The risk was higher in male and black individuals. The study showed that 1%?5% of average-age current live kidney donors might develop ESRD as a result of nephrectomy. The added risk of ESRD resulted in a loss of only 0.126?0.344 remaining life years. Most of the loss of life was predicted to be associated with chronic kidney disease (CKD) not ESRD. Most events occurred 25 or more years after donation. Reducing the increased risk of death associated with CKD had a modest overall effect on the per cent loss of remaining life years (0.72%?1.9%) and QALYs (0.58%?1.33%). Smoking and obesity reduced life expectancy and increased overall lifetime risks of ESRD in non-donors. However the percentage loss of remaining life years from donation was not very different in those with or without these risk factors. Conclusion: Live kidney donation may reduce life expectancy by 0.5?1?year in most donors. The development of ESRD in donors may not be the only measure of risk as most of the predicted loss of life predates ESRD. The study identifies the potential importance of following donors and treating risk factors aggressively to prevent ESRD and to improve donor survival. Twit Text FOAVip Lifetime risks of kidney donation: a medical decision analysis ????BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=28864484 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28864484 #FOAvip English Wikipedia <ref>{{Cite pmid|28864484}}</ref> Lifetime risks of kidney donation: a medical decision analysis #MMPMID28864484 Kiberd BA; Tennankore KK BMJ Open 2017[]; 7 (8): ä PMID28864484show ga Objective: This study estimated the potential loss of life and the lifetime cumulative risk of end-stage renal disease (ESRD) from live kidney donation. Design: Markov medical decision analysis. Setting: USA. Participants: 40-year-old live kidney donors of both sexes and black/white race. Intervention: Live donor nephrectomy. Main outcome and measures: Potential remaining life years lost, quality-adjusted life years (QALYs) lost and added lifetime cumulative risk of ESRD from donation. Results: Overall 0.532?0.884 remaining life years were lost from donating a kidney. This was equivalent to 1.20%?2.34% of remaining life years (or 0.76%?1.51% remaining QALYs). The risk was higher in male and black individuals. The study showed that 1%?5% of average-age current live kidney donors might develop ESRD as a result of nephrectomy. The added risk of ESRD resulted in a loss of only 0.126?0.344 remaining life years. Most of the loss of life was predicted to be associated with chronic kidney disease (CKD) not ESRD. Most events occurred 25 or more years after donation. Reducing the increased risk of death associated with CKD had a modest overall effect on the per cent loss of remaining life years (0.72%?1.9%) and QALYs (0.58%?1.33%). Smoking and obesity reduced life expectancy and increased overall lifetime risks of ESRD in non-donors. However the percentage loss of remaining life years from donation was not very different in those with or without these risk factors. Conclusion: Live kidney donation may reduce life expectancy by 0.5?1?year in most donors. The development of ESRD in donors may not be the only measure of risk as most of the predicted loss of life predates ESRD. The study identifies the potential importance of following donors and treating risk factors aggressively to prevent ESRD and to improve donor survival. äLifetime risks of kidney donation: a medical decision analysis (epmc).pdf DeepDyve Pubget Overpricing