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10.3892/ol.2017.6546 http://scihub22266oqcxt.onion/10.3892/ol.2017.6546 C5588123!5588123!28927026     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncol+Lett 2017 ; 14 (3): 2603-10 Nephropedia Template TP {{tp|p=28927026|t=2017. Associations of tumor suppressor SPARCL1 with cancer progression and prognosis |pdf=|usr=}}{{28927026}} gab.com Text Associations of tumor suppressor SPARCL1 with cancer progression and prognosis JO: Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=28927026 #FOAvip SPARC-like protein 1 (SPARCL1), a member of the family of secreted proteins which is acidic and rich in cysteine, is a potential tumor suppressor gene in most types of tumor. A systemic review and bioinformatics analysis was carried out to determine the associations between SPARCL1 and tumor progression and clinical factors. Downregulation of SPARCL1, thought to be regulated by epigenetic modifications including DNA methylation, serves important functions in tumor progression and development, with its regulatory functions on cell viability, migration, invasion, cell adhesion and drug resistance. Downregulation of SPARCL1 was markedly associated with a poor overall survival rate of patients with one of ?7 solid tumors and predicted increased mortality in patients with one of ?4 distinct tumor types. The present review indicated that SPARCL1 may be a therapeutic target for cancer treatment and a biomarker to determine prognosis. Twit Text FOAVip Associations of tumor suppressor SPARCL1 with cancer progression and prognosis ????Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=28927026 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28927026 #FOAvip English Wikipedia <ref>{{Cite pmid|28927026}}</ref> Associations of tumor suppressor SPARCL1 with cancer progression and prognosis #MMPMID28927026 Li T; Liu X; Yang A; Fu W; Yin F; Zeng X Oncol Lett 2017[Sep]; 14 (3): 2603-10 PMID28927026show ga SPARC-like protein 1 (SPARCL1), a member of the family of secreted proteins which is acidic and rich in cysteine, is a potential tumor suppressor gene in most types of tumor. A systemic review and bioinformatics analysis was carried out to determine the associations between SPARCL1 and tumor progression and clinical factors. Downregulation of SPARCL1, thought to be regulated by epigenetic modifications including DNA methylation, serves important functions in tumor progression and development, with its regulatory functions on cell viability, migration, invasion, cell adhesion and drug resistance. Downregulation of SPARCL1 was markedly associated with a poor overall survival rate of patients with one of ?7 solid tumors and predicted increased mortality in patients with one of ?4 distinct tumor types. The present review indicated that SPARCL1 may be a therapeutic target for cancer treatment and a biomarker to determine prognosis. äAssociations of tumor suppressor SPARCL1 with cancer progression and p(epmc).pdf DeepDyve Pubget Overpricing