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10.19082/4880

http://scihub22266oqcxt.onion/10.19082/4880
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C5587007!5587007!28894549
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suck abstract from ncbi


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pmid28894549      Electron+Physician 2017 ; 9 (7): 4880-5
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  • Predictive value of copeptin as a severity marker of community-acquired pneumonia #MMPMID28894549
  • Mohamed GB; Saed MA; Abdelhakeem AA; Salah K; Saed AM
  • Electron Physician 2017[Jul]; 9 (7): 4880-5 PMID28894549show ga
  • Background: Pneumonia is the leading cause of death in children. Few studies have explored the predictive value of copeptin in pediatric pneumonia. Aim: This study aimed to assess the role of copeptin as a marker of severity of community-acquired pneumonia (CAP). Methods: This prospective case-control study was carried out at Minia University Children?s Hospital in Minia (Egypt) from January to December 2016. Eighty children aged from 2 months to 42 months were enrolled in this study and were classified into group 1 (40 children with clinical, laboratory and radiological evidence of pneumonia) and group 2 (40 apparently healthy control). Serum copeptin level was assayed for all enrolled children. Results: Mean serum copeptin level was significantly higher in pneumonic patients (985.7±619) pg/ml compared to controls (519±308.2) pg/ml (p<0.001). Serum copeptin was significantly elevated in survivors of pneumonia more than non-survivors (p=0.001). Also, copeptin was significantly higher in the group of non-survivors (1811.8±327.1) compared to 745.4±472.5 for survivors (p=0.01). There was a significant positive correlation between serum copeptin levels and the degree of respiratory distress (p=0.02). Conclusion: Copeptin seems a reliable and available predictor marker for assessing the severity and prognosis of pediatric community acquired pneumonia.
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