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2017 ; 6
(7
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Implications of American College of Cardiology/American Heart Association
(ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of
Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of
Community Health Centers
#MMPMID28673901
Akhabue E
; Rittner SS
; Carroll JE
; Crawford PM
; Dant L
; Laws R
; Leo MC
; Puro J
; Persell SD
J Am Heart Assoc
2017[Jul]; 6
(7
): ä PMID28673901
show ga
BACKGROUND: Little is known about statin underutilization among diabetes mellitus
patients cared for in community health centers, which tend to serve
socioeconomically disadvantaged populations. Implications of the American College
of Cardiology/American Heart Association (ACC/AHA) guidelines on preexisting gaps
in statin treatment in this population are unclear. METHODS AND RESULTS: We
included 32 440 adults (45% male, 63% nonwhite, 29% uninsured/Medicaid) aged 40
to 75 years with diabetes mellitus who received care within 16 community health
center groups in 11 states in the Community Health Applied Research Network
during 2013. Statin prescribing was analyzed as a function of concordance with
the National Cholesterol Education Program Adult Treatment Panel 2001 and ACC/AHA
2013 guidelines. More patients' treatments were concordant with the ACC/AHA
(52.8%) versus the National Cholesterol Education Program Adult Treatment
Panel (36.2%) guideline. Female sex was associated with lower concordance for
both (odds ratio [OR] 0.90, CI 0.85-0.94; and OR 0.84, CI 0.80-0.88,
respectively). Being insured, an Asian/Pacific Islander, or primarily Spanish
speaking were associated with greater concordance for both guidelines: 35.5%
(11 526/32 440) were concordant with neither guideline, the majority (79.7%)
having no statin prescribed; 28.2% (9168/32 440) were concordant with ACC/AHA but
not the National Cholesterol Education Program Adult Treatment Panel. 8.7% of
these patients had a low-density lipoprotein cholesterol >160 mg/dL despite
having a moderate- or high-intensity statin prescribed. And 11.6% (3772/32 440)
were concordant with the National Cholesterol Education Program Adult Treatment
Panel but not with ACC/AHA. Most of these patients had a low-density lipoprotein
cholesterol between 70 and 99 mg/dL with no or a low-intensity statin prescribed.
CONCLUSIONS: Opportunities exist to improve cholesterol management in diabetes
mellitus patients in community health centers. Addressing care gaps could improve
cardiovascular disease prevention in this high-risk population.
|*American Heart Association
[MESH]
|Adult
[MESH]
|Aged
[MESH]
|Biomarkers/blood
[MESH]
|Cardiovascular Diseases/diagnosis/ethnology/*prevention & control
[MESH]