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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Am+Heart+Assoc
2017 ; 6
(7
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Outcomes of Patients Presenting With Clinical Indices of Spontaneous Reperfusion
in ST-Elevation Acute Coronary Syndrome Undergoing Deferred Angiography
#MMPMID28743786
Fefer P
; Beigel R
; Atar S
; Aronson D
; Pollak A
; Zahger D
; Asher E
; Iakobishvili Z
; Shlomo N
; Alcalai R
; Einhorn-Cohen M
; Segev A
; Goldenberg I
; Matetzky S
J Am Heart Assoc
2017[Jul]; 6
(7
): ä PMID28743786
show ga
BACKGROUND: Few data are available regarding the optimal management of
ST-elevation myocardial infarction patients with clinically defined spontaneous
reperfusion (SR). We report on the characteristics and outcomes of patients with
SR in the primary percutaneous coronary intervention era, and assess whether
immediate reperfusion can be deferred. METHODS AND RESULTS: Data were drawn from
a prospective nationwide survey, ACSIS (Acute Coronary Syndrome Israeli Survey).
Definition of SR was predefined as both (1) ?70% reduction in ST-segment
elevation on consecutive ECGs and (2) ?70% resolution of pain. Of 2361
consecutive ST-elevation-acute coronary syndrome patients in Killip class 1, 405
(17%) were not treated with primary reperfusion therapy because of SR.
Intervention in SR patients was performed a median of 26 hours after admission.
These patients were compared with the 1956 ST-elevation myocardial infarction
patients who underwent primary reperfusion with a median door-to-balloon of
66 minutes (interquartile range 38-106). Baseline characteristics were similar
except for slightly higher incidence of renal dysfunction and prior angina
pectoris in SR patients. Time from symptom onset to medical contact was
significantly greater in SR patients. Patients with SR had significantly less
in-hospital heart failure (4% versus 11%) and cardiogenic shock (0% versus 2%)
(P<0.01 for all). No significant differences were found in in-hospital mortality
(1% versus 2%), 30-day major cardiac events (4% versus 4%), and mortality at 30
days (1% versus 2%) and 1 year (4% versus 4%). CONCLUSIONS: Patients with
clinically defined SR have a favorable prognosis. Deferring immediate
intervention seems to be safe in patients with clinical indices of spontaneous
reperfusion.