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10.1038/s41467-017-00570-z http://scihub22266oqcxt.onion/10.1038/s41467-017-00570-z C5585379!5585379!28874656     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28874656&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28874656|t=2017. Land-locked mammalian Golgi reveals cargo transport between stable cisternae |pdf=|usr=}}{{28874656}} gab.com Text Land-locked mammalian Golgi reveals cargo transport between stable cisternae JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=28874656 #FOAvip The Golgi is composed of a stack of cis, medial, trans cisternae that are biochemically distinct. The stable compartments model postulates that permanent cisternae communicate through bi-directional vesicles, while the cisternal maturation model postulates that transient cisternae biochemically mature to ensure anterograde transport. Testing either model has been constrained by the diffraction limit of light microscopy, as the cisternae are only 10?20?nm thick and closely stacked in mammalian cells. We previously described the unstacking of Golgi by the ectopic adhesion of Golgi cisternae to mitochondria. Here, we show that cargo processing and transport continue?even when individual Golgi cisternae are separated and ?land-locked? between mitochondria. With the increased spatial separation of cisternae, we show using three-dimensional live imaging that cis-Golgi and trans-Golgi remain stable in their composition and size. Hence, we provide new evidence in support of the stable compartments model in mammalian cells. Twit Text FOAVip Land-locked mammalian Golgi reveals cargo transport between stable cisternae ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=28874656 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28874656 #FOAvip English Wikipedia <ref>{{Cite pmid|28874656}}</ref> Land-locked mammalian Golgi reveals cargo transport between stable cisternae #MMPMID28874656 Dunlop MH; Ernst AM; Schroeder LK; Toomre DK; Lavieu G; Rothman JE Nat Commun 2017[]; 8 (ä): ä PMID28874656show ga The Golgi is composed of a stack of cis, medial, trans cisternae that are biochemically distinct. The stable compartments model postulates that permanent cisternae communicate through bi-directional vesicles, while the cisternal maturation model postulates that transient cisternae biochemically mature to ensure anterograde transport. Testing either model has been constrained by the diffraction limit of light microscopy, as the cisternae are only 10?20?nm thick and closely stacked in mammalian cells. We previously described the unstacking of Golgi by the ectopic adhesion of Golgi cisternae to mitochondria. Here, we show that cargo processing and transport continue?even when individual Golgi cisternae are separated and ?land-locked? between mitochondria. With the increased spatial separation of cisternae, we show using three-dimensional live imaging that cis-Golgi and trans-Golgi remain stable in their composition and size. Hence, we provide new evidence in support of the stable compartments model in mammalian cells. äLand-locked mammalian Golgi reveals cargo transport between stable cis(epmc).pdf DeepDyve Pubget Overpricing