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10.1073/pnas.1709166114 http://scihub22266oqcxt.onion/10.1073/pnas.1709166114 C5584456!5584456!28798064     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (35): 9415-20 Nephropedia Template TP {{tp|p=28798064|t=2017. Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations |pdf=|usr=}}{{28798064}} gab.com Text Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28798064 #FOAvip Epimutations arising from transcriptional mutagenesis have been hypothesized to contribute to viral and bacterial evolution, drug resistance, and age-related diseases, including cancer and neurodegeneration. However, methodology limitations have inhibited progress toward elucidating the contributions of epimutations to cellular evolution and survival in vivo. Recent efforts to overcome these limitations remain constrained by artifacts arising during RNA library preparation. We present accurate RNA consensus sequencing (ARC-seq), an accurate, high-throughput RNA sequencing method that effectively eliminates errors introduced during RNA library preparation and sequencing and represents a major advance over previous methods. ARC-seq will enable investigations of the causal roles of transcriptional fidelity and epimutations in multiple fields, including viral evolution, bacterial resistance, and age-related diseases, such as cancer and neurodegeneration. Twit Text FOAVip Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28798064 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28798064 #FOAvip English Wikipedia <ref>{{Cite pmid|28798064}}</ref> Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations #MMPMID28798064 Reid-Bayliss KS; Loeb LA Proc Natl Acad Sci U S A 2017[Aug]; 114 (35): 9415-20 PMID28798064show ga Epimutations arising from transcriptional mutagenesis have been hypothesized to contribute to viral and bacterial evolution, drug resistance, and age-related diseases, including cancer and neurodegeneration. However, methodology limitations have inhibited progress toward elucidating the contributions of epimutations to cellular evolution and survival in vivo. Recent efforts to overcome these limitations remain constrained by artifacts arising during RNA library preparation. We present accurate RNA consensus sequencing (ARC-seq), an accurate, high-throughput RNA sequencing method that effectively eliminates errors introduced during RNA library preparation and sequencing and represents a major advance over previous methods. ARC-seq will enable investigations of the causal roles of transcriptional fidelity and epimutations in multiple fields, including viral evolution, bacterial resistance, and age-related diseases, such as cancer and neurodegeneration. äAccurate RNA consensus sequencing for high-fidelity detection of trans(epmc).pdf DeepDyve Pubget Overpricing