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10.1084/jem.20161903

http://scihub22266oqcxt.onion/10.1084/jem.20161903
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C5584121!5584121!28798028
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suck abstract from ncbi


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pmid28798028      J+Exp+Med 2017 ; 214 (9): 2733-58
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  • PTPN2 regulates T cell lineage commitment and ?? versus ?? specification #MMPMID28798028
  • Wiede F; Dudakov JA; Lu KH; Dodd GT; Butt T; Godfrey DI; Strasser A; Boyd RL; Tiganis T
  • J Exp Med 2017[Sep]; 214 (9): 2733-58 PMID28798028show ga
  • During early thymocyte development, coordinated JAK/STAT5 and SFK/pre-TCR signaling is critical for T cell lineage commitment and ?? versus ?? specification. Wiede et al. show a role for the tyrosine phosphatase PTPN2 in attenuating SRC family kinase LCK and STAT5 signaling to regulate ?? and ?? T cell development.
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