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10.1089/jop.2016.0137 http://scihub22266oqcxt.onion/10.1089/jop.2016.0137 C5583554!5583554!28051353     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Ocul+Pharmacol+Ther 2017 ; 33 (4): 285-9 Nephropedia Template TP {{tp|p=28051353|t=2017. Panax Notoginseng Saponin Controls IL-17 Expression in Helper T Cells |pdf=|usr=}}{{28051353}} gab.com Text Panax Notoginseng Saponin Controls IL-17 Expression in Helper T Cells JO: J Ocul Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=28051353 #FOAvip Purpose: Panax Notoginseng, a traditional Chinese medicine, is known as an anti-inflammatory herb. However, the molecular mechanism by which it controls helper T cell mediated immune responses is largely unknown.Methods: Naive CD4+ T cells isolated from healthy donors, patients with Behcet's disease, and C57BL/6 mice were polarized into Th1, Th17, and Treg cells. Proliferation and cytokine expression were measured in these cells with the presence or absence of Panax Notoginseng saponins (PNS). Genomewide expression profiles of Th1, Th17, and Treg cells were assessed using Affymetrix microarray analysis.Results: We found that PNS control the proliferation and differentiation of Th17 cells by globally downregulating the expression of inflammatory cytokines and cell cycle genes.Conclusions: These findings demonstrated that PNS function as an anti-inflammatory agent through directly targeting Th17 cell mediated immune response. Twit Text FOAVip Panax Notoginseng Saponin Controls IL-17 Expression in Helper T Cells ????J Ocul Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=28051353 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28051353 #FOAvip English Wikipedia <ref>{{Cite pmid|28051353}}</ref> Panax Notoginseng Saponin Controls IL-17 Expression in Helper T Cells #MMPMID28051353 Wei JR; Wen X; Bible PW; Li Z; Nussenblatt RB; Wei L J Ocul Pharmacol Ther 2017[May]; 33 (4): 285-9 PMID28051353show ga Purpose: Panax Notoginseng, a traditional Chinese medicine, is known as an anti-inflammatory herb. However, the molecular mechanism by which it controls helper T cell mediated immune responses is largely unknown.Methods: Naive CD4+ T cells isolated from healthy donors, patients with Behcet's disease, and C57BL/6 mice were polarized into Th1, Th17, and Treg cells. Proliferation and cytokine expression were measured in these cells with the presence or absence of Panax Notoginseng saponins (PNS). Genomewide expression profiles of Th1, Th17, and Treg cells were assessed using Affymetrix microarray analysis.Results: We found that PNS control the proliferation and differentiation of Th17 cells by globally downregulating the expression of inflammatory cytokines and cell cycle genes.Conclusions: These findings demonstrated that PNS function as an anti-inflammatory agent through directly targeting Th17 cell mediated immune response. äPanax Notoginseng Saponin Controls IL-17 Expression in Helper T Cells (epmc).pdf DeepDyve Pubget Overpricing