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10.18632/oncotarget.17255 http://scihub22266oqcxt.onion/10.18632/oncotarget.17255 C5581149!5581149!28881850     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28881850.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Oncotarget 2017 ; 8 (32): 53780-90 Nephropedia Template TP {{tp|p=28881850|t=2017. Transforming growth factor ?: A potential biomarker and therapeutic target of ventricular remodeling |pdf=|usr=}}{{28881850}} gab.com Text Transforming growth factor : A potential biomarker and therapeutic target of ventricular remodeling JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28881850 #FOAvip Transforming growth factor ? (TGF-?) is a multifunctional cytokine that is synthesized by many types of cells and regulates the cell cycle. Increasing evidence has led to TGF-? receiving increased and deserved attention in recent years because it may play a potentially novel and critical role in the development and progression of myocardial fibrosis and the subsequent progress of ventricular remodeling (VR). Numerous studies have highlighted a crucial role of TGF-? in VR and suggest potential therapeutic targets of the TGF-? signaling pathways for VR. Changes in TGF-? activity may elicit anti-VR activity and may serve as a novel therapeutic target for VR therapy. This review we discusses the smad-dependent signaling pathway, such as TGF-?/Smads, TGF-?/Sirtuins, TGF-?/BMP, TGF-?/miRNAs, TGF-?/MAPK, and Smad-independent signaling pathway of TGF-?, such as TGF-?/PI3K/Akt, TGF-?/Rho/ROCK,TGF-?/Wnt/?-catenin in the cardiac fibrosis and subsequent progression of VR. Furthermore, agonists and antagonists of TGF-? as potential therapeutic targets in VR are also described. Twit Text FOAVip Transforming growth factor : A potential biomarker and therapeutic target of ventricular remodeling ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28881850 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28881850 #FOAvip English Wikipedia <ref>{{Cite pmid|28881850}}</ref> Transforming growth factor ?: A potential biomarker and therapeutic target of ventricular remodeling #MMPMID28881850 Ma Y; Zou H; Zhu XX; Pang J; Xu Q; Jin QY; Ding YH; Zhou B; Huang DS Oncotarget 2017[Aug]; 8 (32): 53780-90 PMID28881850show ga Transforming growth factor ? (TGF-?) is a multifunctional cytokine that is synthesized by many types of cells and regulates the cell cycle. Increasing evidence has led to TGF-? receiving increased and deserved attention in recent years because it may play a potentially novel and critical role in the development and progression of myocardial fibrosis and the subsequent progress of ventricular remodeling (VR). Numerous studies have highlighted a crucial role of TGF-? in VR and suggest potential therapeutic targets of the TGF-? signaling pathways for VR. Changes in TGF-? activity may elicit anti-VR activity and may serve as a novel therapeutic target for VR therapy. This review we discusses the smad-dependent signaling pathway, such as TGF-?/Smads, TGF-?/Sirtuins, TGF-?/BMP, TGF-?/miRNAs, TGF-?/MAPK, and Smad-independent signaling pathway of TGF-?, such as TGF-?/PI3K/Akt, TGF-?/Rho/ROCK,TGF-?/Wnt/?-catenin in the cardiac fibrosis and subsequent progression of VR. Furthermore, agonists and antagonists of TGF-? as potential therapeutic targets in VR are also described. äTransforming growth factor ?: A potential biomarker and therapeutic ta(epmc).pdf DeepDyve Pubget Overpricing