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10.1007/s00395-017-0645-y http://scihub22266oqcxt.onion/10.1007/s00395-017-0645-y C5579185!5579185!28861604     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Basic+Res+Cardiol 2017 ; 112 (5): ä Nephropedia Template TP {{tp|p=28861604|t=2017. Cardiac optogenetics: using light to monitor cardiac physiology |pdf=|usr=}}{{28861604}} gab.com Text Cardiac optogenetics: using light to monitor cardiac physiology JO: Basic Res Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28861604 #FOAvip Our current understanding of cardiac excitation and its coupling to contraction is largely based on ex vivo studies utilising fluorescent organic dyes to assess cardiac action potentials and signal transduction. Recent advances in optogenetic sensors open exciting new possibilities for cardiac research and allow us to answer research questions that cannot be addressed using the classic organic dyes. Especially thrilling is the possibility to use optogenetic sensors to record parameters of cardiac excitation and contraction in vivo. In addition, optogenetics provide a high spatial resolution, as sensors can be coupled to motifs and targeted to specific cell types and subcellular domains of the heart. In this review, we will give a comprehensive overview of relevant optogenetic sensors, how they can be utilised in cardiac research and how they have been applied in cardiac research up to now. Twit Text FOAVip Cardiac optogenetics: using light to monitor cardiac physiology ????Basic Res Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28861604 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28861604 #FOAvip English Wikipedia <ref>{{Cite pmid|28861604}}</ref> Cardiac optogenetics: using light to monitor cardiac physiology #MMPMID28861604 Koopman CD; Zimmermann WH; Knöpfel T; de Boer TP Basic Res Cardiol 2017[]; 112 (5): ä PMID28861604show ga Our current understanding of cardiac excitation and its coupling to contraction is largely based on ex vivo studies utilising fluorescent organic dyes to assess cardiac action potentials and signal transduction. Recent advances in optogenetic sensors open exciting new possibilities for cardiac research and allow us to answer research questions that cannot be addressed using the classic organic dyes. Especially thrilling is the possibility to use optogenetic sensors to record parameters of cardiac excitation and contraction in vivo. In addition, optogenetics provide a high spatial resolution, as sensors can be coupled to motifs and targeted to specific cell types and subcellular domains of the heart. In this review, we will give a comprehensive overview of relevant optogenetic sensors, how they can be utilised in cardiac research and how they have been applied in cardiac research up to now. äCardiac optogenetics: using light to monitor cardiac physiology (epmc).pdf DeepDyve Pubget Overpricing