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10.1042/BSR20170747 http://scihub22266oqcxt.onion/10.1042/BSR20170747 C5577172!5577172 !28784933     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28784933 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Biosci+Rep 2017 ; 37 (4 ): ? Nephropedia Template TP {{tp|p=28784933 |t=2017. Association between the TGF-?1 polymorphisms and chronic obstructive pulmonary disease: a meta-analysis |pdf=|usr=}}{{28784933 }} gab.com Text Association between the TGF- 1 polymorphisms and chronic obstructive pulmonary disease: a meta-analysis JO: Biosci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28784933 #FOAvip It has been hypothesized that polymorphisms in the transforming growth factor-?1 (TGF-?1) gene on chromosome 19 modify the risk for chronic obstructive pulmonary disease (COPD). However, results from previous studies are contradictory. We therefore conducted a meta-analysis of published case-control studies on the association between five common TGF-?1 polymorphisms (rs1982073, rs1800469, rs2241712, rs6957, and rs2241718) and COPD risk. Data sources were Pubmed, Scopus, ISI Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang databases. Twelve studies including 6749 participants were reviewed and analyzed. For the TGF-?1 polymorphism rs1982073, the results indicted that the C allele was associated with decreased risk of COPD in Caucasians (odds ratio (OR) =0.79, 95% confidence interval (CI): 0.64-0.99, P=0.038) but not in Asians (OR =0.95, 95% CI: 0.71-1.28, P=0.741). No associations with COPD were identified for other polymorphisms evaluated in the present study including rs1800469 (T allele compared with C allele, OR =0.89, 95% CI: 0.77-1.02, P=0.099), rs2241712 (A allele compared with G allele, OR =1.03, 95% CI: 0.89-1.20, P=0.666), rs6957 (A allele compared with G allele, OR =1.14, 95% CI: 0.95-1.36, P=0.160), and rs2241718 (C allele compared with T allele, OR =0.95, 95% CI: 0.79-1.14, P=0.571). In conclusion, this meta-analysis showed that the C allele of rs1982073 was protective against COPD in Caucasians but not in Asians, whereas there was no association of rs1800469, rs2241712, rs6957, and rs2241718 with COPD. Twit Text FOAVip Association between the TGF- 1 polymorphisms and chronic obstructive pulmonary disease: a meta-analysis ????Biosci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28784933 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28784933 #FOAvip English Wikipedia <ref>{{Cite pmid|28784933 }}</ref> Association between the TGF-?1 polymorphisms and chronic obstructive pulmonary disease: a meta-analysis #MMPMID28784933 Liao N ; Zhao H ; Chen ML ; Xie ZF Biosci Rep 2017[Aug]; 37 (4 ): ? PMID28784933 show ga It has been hypothesized that polymorphisms in the transforming growth factor-?1 (TGF-?1) gene on chromosome 19 modify the risk for chronic obstructive pulmonary disease (COPD). However, results from previous studies are contradictory. We therefore conducted a meta-analysis of published case-control studies on the association between five common TGF-?1 polymorphisms (rs1982073, rs1800469, rs2241712, rs6957, and rs2241718) and COPD risk. Data sources were Pubmed, Scopus, ISI Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang databases. Twelve studies including 6749 participants were reviewed and analyzed. For the TGF-?1 polymorphism rs1982073, the results indicted that the C allele was associated with decreased risk of COPD in Caucasians (odds ratio (OR) =0.79, 95% confidence interval (CI): 0.64-0.99, P=0.038) but not in Asians (OR =0.95, 95% CI: 0.71-1.28, P=0.741). No associations with COPD were identified for other polymorphisms evaluated in the present study including rs1800469 (T allele compared with C allele, OR =0.89, 95% CI: 0.77-1.02, P=0.099), rs2241712 (A allele compared with G allele, OR =1.03, 95% CI: 0.89-1.20, P=0.666), rs6957 (A allele compared with G allele, OR =1.14, 95% CI: 0.95-1.36, P=0.160), and rs2241718 (C allele compared with T allele, OR =0.95, 95% CI: 0.79-1.14, P=0.571). In conclusion, this meta-analysis showed that the C allele of rs1982073 was protective against COPD in Caucasians but not in Asians, whereas there was no association of rs1800469, rs2241712, rs6957, and rs2241718 with COPD. |*Genetic Predisposition to Disease [MESH] |*Polymorphism, Single Nucleotide [MESH] |Female [MESH] |Humans [MESH] |Male [MESH] |Pulmonary Disease, Chronic Obstructive/*genetics [MESH] |Transforming Growth Factor beta1/*genetics [MESH]Association between the TGF-?1 polymorphisms and chronic obstructive p(epmc).pdf DeepDyve Pubget Overpricing