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Quantum dot light emitting devices for photomedical applications #MMPMID28867926
Chen H; He J; Lanzafame R; Stadler I; Hamidi HE; Liu H; Celli J; Hamblin MR; Huang Y; Oakley E; Shafirstein G; Chung HK; Wu ST; Dong Y
J Soc Inf Disp 2017[Mar]; 25 (3): 177-84 PMID28867926show ga
While OLEDs have struggled to find a niche lighting application that can fully take advantage of their unique form factors as thin, flexible, lightweight and uniformly large-area luminaire, photomedical researchers have been in search of low-cost, effective illumination devices with such form factors that could facilitate widespread clinical applications of photodynamic therapy (PDT) or photobiomodulation (PBM). Although existing OLEDs with either fluorescent or phosphorescent emitters cannot achieve the required high power density at the right wavelength windows for photomedicine, the recently developed ultrabright and efficient deep red quantum dot light emitting devices (QLEDs) can nicely fit into this niche. Here, we report for the first time the in-vitro study to demonstrate that this QLED-based photomedical approach could increase cell metabolism over control systems for PBM and kill cancerous cells efficiently for PDT. The perspective of developing wavelength-specific, flexible QLEDs for two critical photomedical fields (wound repair and cancer treatment) will be presented with their potential impacts summarized. The work promises to generate flexible QLED-based light sources that could enable the widespread use and clinical acceptance of photomedical strategies including PDT and PBM.
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J+Soc+Inf+Disp 2017 ; 25 (3): 177-84
