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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Maedica+(Bucur) 2017 ; 12 (1): 55-8 Nephropedia Template TP
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Correlation Between Idiopathic Nephrotic Syndrome and Atopy in Children ? Short Review #MMPMID28878838
BERGHEA EC; BALGRADEAN M; POPA IL
Maedica (Bucur) 2017[Jan]; 12 (1): 55-8 PMID28878838show ga
The idiopathic nephrotic syndrome is a common chronic kidney diseases in children defined by the association of massive proteinuria and hypoalbuminemia in a relapsing/remission course, with histological aspect of minimal changes (also called minimal change disease) in the majority of the cases, but its pathogenesis remains not very well known. Clinical and immunological studies have consistently shown a relationship between atopic diathesis, immunoglobulin E and cytokines involved in immunoglobulin E synthesis and idiopathic nephrotic syndrome. Additional research is necessary to clarify this relationship and to explore the contribution of allergic disease to the development of nephrotic syndrome and to identify potential new strategies of diagnosis and treatment.