Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.celrep.2017.08.007 http://scihub22266oqcxt.onion/10.1016/j.celrep.2017.08.007 C5574064!5574064!28834740     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2017 ; 20 (8): 1755-64 Nephropedia Template TP {{tp|p=28834740|t=2017. Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination |pdf=|usr=}}{{28834740}} gab.com Text Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=28834740 #FOAvip The role of the neurovascular niche in CNS myelin regeneration is incompletely understood. Here, we show that, upon demyelination, CNS-resident pericytes (PCs) proliferate, and parenchymal non-vessel-associated PC-like cells (PLCs) rapidly develop. During remyelination, mature oligodendrocytes were found in close proximity to PCs. In Pdgfbret/ret mice, which have reduced PC numbers, oligodendrocyte progenitor cell (OPC) differentiation was delayed, although remyelination proceeded to completion. PC-conditioned medium accelerated and enhanced OPC differentiation in vitro and increased the rate of remyelination in an ex vivo cerebellar slice model of demyelination. We identified Lama2 as a PC-derived factor that promotes OPC differentiation. Thus, the functional role of PCs is not restricted to vascular homeostasis but includes the modulation of adult CNS progenitor cells involved in regeneration. Twit Text FOAVip Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=28834740 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28834740 #FOAvip English Wikipedia <ref>{{Cite pmid|28834740}}</ref> Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination #MMPMID28834740 De La Fuente AG; Lange S; Silva ME; Gonzalez GA; Tempfer H; van Wijngaarden P; Zhao C; Di Canio L; Trost A; Bieler L; Zaunmair P; Rotheneichner P; O?Sullivan A; Couillard-Despres S; Errea O; Mäe MA; Andrae J; He L; Keller A; Bátiz LF; Betsholtz C; Aigner L; Franklin RJ; Rivera FJ Cell Rep 2017[Aug]; 20 (8): 1755-64 PMID28834740show ga The role of the neurovascular niche in CNS myelin regeneration is incompletely understood. Here, we show that, upon demyelination, CNS-resident pericytes (PCs) proliferate, and parenchymal non-vessel-associated PC-like cells (PLCs) rapidly develop. During remyelination, mature oligodendrocytes were found in close proximity to PCs. In Pdgfbret/ret mice, which have reduced PC numbers, oligodendrocyte progenitor cell (OPC) differentiation was delayed, although remyelination proceeded to completion. PC-conditioned medium accelerated and enhanced OPC differentiation in vitro and increased the rate of remyelination in an ex vivo cerebellar slice model of demyelination. We identified Lama2 as a PC-derived factor that promotes OPC differentiation. Thus, the functional role of PCs is not restricted to vascular homeostasis but includes the modulation of adult CNS progenitor cells involved in regeneration. äPericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation du(epmc).pdf DeepDyve Pubget Overpricing