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10.2217/rme-2016-0141 http://scihub22266oqcxt.onion/10.2217/rme-2016-0141 C5572980!5572980 !28524773     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28524773 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Regen+Med 2017 ; 12 (3 ): 249-261 Nephropedia Template TP {{tp|p=28524773 |t=2017. The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft |pdf=|usr=}}{{28524773 }} gab.com Text The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft JO: Regen Med http://www.kidney.de/pget.php?&tw=1&pmid=28524773 #FOAvip AIM: Inflammatory myeloid lineage cells mediate neotissue formation in tissue-engineered vascular grafts, but the molecular mechanism is not completely understood. We examined the role of vasculogenic PDGF-B in tissue-engineered vascular graft neotissue development. MATERIALS & METHODS: Myeloid cell-specific PDGF-B knockout mice (PDGF-KO) were generated using bone marrow transplantation, and scaffolds were implanted as inferior vena cava interposition grafts in either PDGF-KO or wild-type mice. RESULTS: After 2 weeks, grafts from PDGF-KO mice had more remaining scaffold polymer and less intimal neotissue development. Increased macrophage apoptosis, decreased smooth muscle cell proliferation and decreased collagen content was also observed. CONCLUSION: Myeloid cell-derived PDGF contributes to vascular neotissue formation by regulating macrophage apoptosis, smooth muscle cell proliferation and extracellular matrix deposition. Twit Text FOAVip The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft ????Regen Med http://www.kidney.de/pget.php?&tw=1&pmid=28524773 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28524773 #FOAvip English Wikipedia <ref>{{Cite pmid|28524773 }}</ref> The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft #MMPMID28524773 Onwuka E ; Best C ; Sawyer A ; Yi T ; Heuer E ; Sams M ; Wiet M ; Zheng H ; Kyriakides T ; Breuer C Regen Med 2017[Apr]; 12 (3 ): 249-261 PMID28524773 show ga AIM: Inflammatory myeloid lineage cells mediate neotissue formation in tissue-engineered vascular grafts, but the molecular mechanism is not completely understood. We examined the role of vasculogenic PDGF-B in tissue-engineered vascular graft neotissue development. MATERIALS & METHODS: Myeloid cell-specific PDGF-B knockout mice (PDGF-KO) were generated using bone marrow transplantation, and scaffolds were implanted as inferior vena cava interposition grafts in either PDGF-KO or wild-type mice. RESULTS: After 2 weeks, grafts from PDGF-KO mice had more remaining scaffold polymer and less intimal neotissue development. Increased macrophage apoptosis, decreased smooth muscle cell proliferation and decreased collagen content was also observed. CONCLUSION: Myeloid cell-derived PDGF contributes to vascular neotissue formation by regulating macrophage apoptosis, smooth muscle cell proliferation and extracellular matrix deposition. |*Bioprosthesis [MESH] |*Blood Vessel Prosthesis [MESH] |*Tissue Engineering [MESH] |Animals [MESH] |Cell Differentiation [MESH] |Lymphokines/genetics/*metabolism [MESH] |Mice [MESH] |Mice, Knockout [MESH] |Myeloid Cells/*metabolism/pathology [MESH] |Myocytes, Smooth Muscle/metabolism/pathology [MESH] |Neointima/genetics/*metabolism/pathology [MESH] |Platelet-Derived Growth Factor/genetics/*metabolism [MESH]The role of myeloid cell-derived PDGF-B in neotissue formation in a (epmc).pdf DeepDyve Pubget Overpricing