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Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Emerg+Infect+Dis 2017 ; 23 (9): 1564-7 Nephropedia Template TP
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Emergence of Plasmid-Mediated Fosfomycin-Resistance Genes among Escherichia coli Isolates, France #MMPMID28820368
Benzerara Y; Gallah S; Hommeril B; Genel N; Decré D; Rottman M; Arlet G
Emerg Infect Dis 2017[Sep]; 23 (9): 1564-7 PMID28820368show ga
FosA, a glutathione S-transferase that inactivates fosfomycin, has been reported as the cause of enzymatic resistance to fosfomycin. We show that multiple lineages of FosA-producing extended spectrum ?-lactamase Escherichia coli have circulated in France since 2012, potentially reducing the efficacy of fosfomycin in treating infections with antimicrobial drug?resistant gram-negative bacilli.