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10.1155/2017/5348928

http://scihub22266oqcxt.onion/10.1155/2017/5348928
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C5572623!5572623!28884026
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suck abstract from ncbi


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pmid28884026      J+Obes 2017 ; 2017 (ä): ä
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  • Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management #MMPMID28884026
  • Chagot C; Blonski M; Machu JL; Bracard S; Lacour JC; Richard S
  • J Obes 2017[]; 2017 (ä): ä PMID28884026show ga
  • Background: Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. Methods: We retrospectively collected data from all patients diagnosed and managed for IIH in our university center from January 2001 to December 2016. Results: Seventy-nine patients were diagnosed with IIH. Bilateral transverse sinus stenosis (TSS) was found in 74% of the population. Visual outcome at 6 months was poor for 46% of patients, including all patients presenting weight gain of at least 5% since diagnosis (p < 0.001), whereas mean body mass index at diagnosis was not different between patients with poor versus good outcome (32.9 ± 7.7 versus 34.6 ± 9.4?kg·m?2). Other significant factors of poor prognosis were bilateral TSS (OR = 5.2; 95 CI: 1.24?24.9; p = 0.024). Thirteen patients with poor outcome after 6-month assessment underwent unilateral TSS stenting leading to visual improvement in 11 cases. Conclusion: Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. Consequently, first-line treatment must include dietary measures to control weight. Unilateral stenting appears to be a safe second-line treatment option for patients with bilateral TSS.
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