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10.21873/cgp.20032 http://scihub22266oqcxt.onion/10.21873/cgp.20032 C5572299!5572299!28647695     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Genomics+Proteomics 2017 ; 14 (4): 211-8 Nephropedia Template TP {{tp|p=28647695|t=2017. The Warburg Effect and Mass Spectrometry-based Proteomic Analysis |pdf=|usr=}}{{28647695}} gab.com Text The Warburg Effect and Mass Spectrometry-based Proteomic Analysis JO: Cancer Genomics Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=28647695 #FOAvip Compared to normal cells, cancer cells have a unique metabolism by performing lactic acid fermentation in the presence of oxygen, also known as the Warburg effect. Researchers have proposed several hypotheses to elucidate the phenomenon, but the mechanism is still an enigma. In this review, we discuss three typical models, such as ?damaged mitochondria?, ?adaptation to hypoxia?, and ?cell proliferation requirement?, as well as contributions from mass spectrometry analysis toward our understanding of the Warburg effect. Mass spectrometry analysis supports the ?adaptation to hypoxia? model that cancer cells are using quasi-anaerobic fermentation to reduce oxygen consumption in vivo. We further propose that hypoxia is an early event and it plays a crucial role in carcinoma initiation and development. Twit Text FOAVip The Warburg Effect and Mass Spectrometry-based Proteomic Analysis ????Cancer Genomics Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=28647695 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28647695 #FOAvip English Wikipedia <ref>{{Cite pmid|28647695}}</ref> The Warburg Effect and Mass Spectrometry-based Proteomic Analysis #MMPMID28647695 ZHOU W; LIOTTA AL; PETRICOIN FE Cancer Genomics Proteomics 2017[Jul]; 14 (4): 211-8 PMID28647695show ga Compared to normal cells, cancer cells have a unique metabolism by performing lactic acid fermentation in the presence of oxygen, also known as the Warburg effect. Researchers have proposed several hypotheses to elucidate the phenomenon, but the mechanism is still an enigma. In this review, we discuss three typical models, such as ?damaged mitochondria?, ?adaptation to hypoxia?, and ?cell proliferation requirement?, as well as contributions from mass spectrometry analysis toward our understanding of the Warburg effect. Mass spectrometry analysis supports the ?adaptation to hypoxia? model that cancer cells are using quasi-anaerobic fermentation to reduce oxygen consumption in vivo. We further propose that hypoxia is an early event and it plays a crucial role in carcinoma initiation and development. äThe Warburg Effect and Mass Spectrometry-based Proteomic Analysis (epmc).pdf DeepDyve Pubget Overpricing