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10.1097/MD.0000000000007708 http://scihub22266oqcxt.onion/10.1097/MD.0000000000007708 C5571997!5571997 !28834875     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28834875 &cmd=llinks): Failed to open stream: HTTP request failed! 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Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohort study |pdf=|usr=}}{{28834875 }} gab.com Text Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohort study JO: Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=28834875 #FOAvip Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that if left untreated may lead to the development of cirrhosis. Previous studies on AIH patients have suggested that fibrosis and even cirrhosis can be reversed by medical treatment. The aim of this study was to evaluate the efficacy of medical treatment for protection of developing fibrosis and cirrhosis.A total of 258 liver biopsies from 101 patients (72 women, 29 men) were analyzed by a single pathologist and classified according to the Ishak grading (inflammation) and staging (fibrosis) system. Liver histology was stratified according to the temporal changes of fibrosis stage (increased, decreased, or stable), and groups were compared.Complete or partial response to medical treatment was 94.9%. Reduction of fibrosis stage from the first to the last biopsy was seen in 63 patients (62.4%). We found an association between a reduction in the fibrosis stage and continuous glucocorticoid medication, as well as lowered scores of inflammation at last biopsy. Twenty-one patients had cirrhosis (Ishak stage 6) at least in one of the previous biopsies, but only 5 patients at the last biopsy.Histological improvement is common in AIH patients that respond to medical treatment, and a reduction or stabilization of fibrosis stage occurs in about 2/3 of such patients. Twit Text FOAVip Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohort study ????Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=28834875 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28834875 #FOAvip English Wikipedia <ref>{{Cite pmid|28834875 }}</ref> Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohort study #MMPMID28834875 Borssén ÅD ; Palmqvist R ; Kechagias S ; Marschall HU ; Bergquist A ; Rorsman F ; Weiland O ; Verbaan H ; Nyhlin N ; Nilsson E ; Werner M Medicine (Baltimore) 2017[Aug]; 96 (34 ): e7708 PMID28834875 show ga Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that if left untreated may lead to the development of cirrhosis. Previous studies on AIH patients have suggested that fibrosis and even cirrhosis can be reversed by medical treatment. The aim of this study was to evaluate the efficacy of medical treatment for protection of developing fibrosis and cirrhosis.A total of 258 liver biopsies from 101 patients (72 women, 29 men) were analyzed by a single pathologist and classified according to the Ishak grading (inflammation) and staging (fibrosis) system. Liver histology was stratified according to the temporal changes of fibrosis stage (increased, decreased, or stable), and groups were compared.Complete or partial response to medical treatment was 94.9%. Reduction of fibrosis stage from the first to the last biopsy was seen in 63 patients (62.4%). We found an association between a reduction in the fibrosis stage and continuous glucocorticoid medication, as well as lowered scores of inflammation at last biopsy. Twenty-one patients had cirrhosis (Ishak stage 6) at least in one of the previous biopsies, but only 5 patients at the last biopsy.Histological improvement is common in AIH patients that respond to medical treatment, and a reduction or stabilization of fibrosis stage occurs in about 2/3 of such patients. |Adolescent [MESH] |Adult [MESH] |Aged [MESH] |Biopsy [MESH] |Child [MESH] |Disease Progression [MESH] |Female [MESH] |Hepatitis, Autoimmune/complications/*pathology [MESH] |Hospitals, University [MESH] |Humans [MESH] |Inflammation/etiology/*pathology [MESH] |Liver Cirrhosis/etiology/*pathology [MESH] |Male [MESH] |Middle Aged [MESH] |Severity of Illness Index [MESH] |Sweden [MESH]Histological improvement of liver fibrosis in well-treated patients wi(epmc).pdf DeepDyve Pubget Overpricing