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10.20892/j.issn.2095-3941.2017.0029 http://scihub22266oqcxt.onion/10.20892/j.issn.2095-3941.2017.0029 C5570602!5570602 !28884042     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28884042 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cancer+Biol+Med 2017 ; 14 (3 ): 254-270 Nephropedia Template TP {{tp|p=28884042 |t=2017. Aberrant control of NF-?B in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode |pdf=|usr=}}{{28884042 }} gab.com Text Aberrant control of NF- B in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode JO: Cancer Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=28884042 #FOAvip The role of the transcription factor NF-?B in shaping the cancer microenvironment is becoming increasingly clear. Inflammation alters the activity of enzymes that modulate NF-?B function, and causes extensive changes in genomic chromatin that ultimately drastically alter cell-specific gene expression. NF-?B regulates the expression of cytokines and adhesion factors that control interactions among adjacent cells. As such, NF-?B fine tunes tissue cellular composition, as well as tissues' interactions with the immune system. Therefore, NF-?B changes the cell response to hormones and to contact with neighboring cells. Activating NF-?B confers transcriptional and phenotypic plasticity to a cell and thereby enables profound local changes in tissue function and composition. Research suggests that the regulation of NF-?B target genes is specifically altered in cancer. Such alterations occur not only due to mutations of NF-?B regulatory proteins, but also because of changes in the activity of specific proteostatic modules and metabolic pathways. This article describes the molecular mode of NF-?B regulation with a few characteristic examples of target genes. Twit Text FOAVip Aberrant control of NF- B in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode ????Cancer Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=28884042 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28884042 #FOAvip English Wikipedia <ref>{{Cite pmid|28884042 }}</ref> Aberrant control of NF-?B in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode #MMPMID28884042 Vlahopoulos SA Cancer Biol Med 2017[Aug]; 14 (3 ): 254-270 PMID28884042 show ga The role of the transcription factor NF-?B in shaping the cancer microenvironment is becoming increasingly clear. Inflammation alters the activity of enzymes that modulate NF-?B function, and causes extensive changes in genomic chromatin that ultimately drastically alter cell-specific gene expression. NF-?B regulates the expression of cytokines and adhesion factors that control interactions among adjacent cells. As such, NF-?B fine tunes tissue cellular composition, as well as tissues' interactions with the immune system. Therefore, NF-?B changes the cell response to hormones and to contact with neighboring cells. Activating NF-?B confers transcriptional and phenotypic plasticity to a cell and thereby enables profound local changes in tissue function and composition. Research suggests that the regulation of NF-?B target genes is specifically altered in cancer. Such alterations occur not only due to mutations of NF-?B regulatory proteins, but also because of changes in the activity of specific proteostatic modules and metabolic pathways. This article describes the molecular mode of NF-?B regulation with a few characteristic examples of target genes. äAberrant control of NF-?B in cancer permits transcriptional and phenot(epmc).pdf DeepDyve Pubget Overpricing