Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1002/adhm.201700383 http://scihub22266oqcxt.onion/10.1002/adhm.201700383 C5568941!5568941!28512791     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Adv+Healthc+Mater 2017 ; 6 (16): ä Nephropedia Template TP {{tp|p=28512791|t=2017. Peptide?Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite?Mediated Nitration |pdf=|usr=}}{{28512791}} gab.com Text Peptide Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite Mediated Nitration JO: Adv Healthc Mater http://www.kidney.de/pget.php?&tw=1&pmid=28512791 #FOAvip Nitric oxide (NO) is a free radical signaling molecule that plays a crucial role in modulating physiological homeostasis across multiple biological systems. NO dysregulation is linked to the pathogenesis of multiple diseases; therefore, its quantification is important for understanding pathophysiological processes. The detection of NO is challenging, typically limited by its reactive nature and short half?life. Additionally, the presence of interfering analytes and accessibility to biological fluids in the native tissues make the measurement technically challenging and often unreliable. Here, a bio?inspired peptide?based NO sensor is developed, which detects NO?derived oxidants, predominately peroxynitrite?mediated nitration of tyrosine residues. It is demonstrated that these peptide?based NO sensors can detect peroxynitrite?mediated nitration in response to physiological shear stress by endothelial cells in vitro. Using the peptide?conjugated fluorescent particle immunoassay, peroxynitrite?mediated nitration activity with a detection limit of ?100 × 10?9m is detected. This study envisions that the NO detection platform can be applied to a multitude of applications including monitoring of NO activity in healthy and diseased tissues, localized detection of NO production of specific cells, and cell?based/therapeutic screening of peroxynitrite levels to monitor pronitroxidative stress in biological samples. Twit Text FOAVip Peptide Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite Mediated Nitration ????Adv Healthc Mater http://www.kidney.de/pget.php?&tw=1&pmid=28512791 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28512791 #FOAvip English Wikipedia <ref>{{Cite pmid|28512791}}</ref> Peptide?Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite?Mediated Nitration #MMPMID28512791 Chang JYH; Chow LW; Dismuke WM; Ethier CR; Stevens MM; Stamer WD; Overby DR Adv Healthc Mater 2017[Aug]; 6 (16): ä PMID28512791show ga Nitric oxide (NO) is a free radical signaling molecule that plays a crucial role in modulating physiological homeostasis across multiple biological systems. NO dysregulation is linked to the pathogenesis of multiple diseases; therefore, its quantification is important for understanding pathophysiological processes. The detection of NO is challenging, typically limited by its reactive nature and short half?life. Additionally, the presence of interfering analytes and accessibility to biological fluids in the native tissues make the measurement technically challenging and often unreliable. Here, a bio?inspired peptide?based NO sensor is developed, which detects NO?derived oxidants, predominately peroxynitrite?mediated nitration of tyrosine residues. It is demonstrated that these peptide?based NO sensors can detect peroxynitrite?mediated nitration in response to physiological shear stress by endothelial cells in vitro. Using the peptide?conjugated fluorescent particle immunoassay, peroxynitrite?mediated nitration activity with a detection limit of ?100 × 10?9m is detected. This study envisions that the NO detection platform can be applied to a multitude of applications including monitoring of NO activity in healthy and diseased tissues, localized detection of NO production of specific cells, and cell?based/therapeutic screening of peroxynitrite levels to monitor pronitroxidative stress in biological samples. äPeptide?Functionalized Fluorescent Particles for In Situ Detection of (epmc).pdf DeepDyve Pubget Overpricing