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10.11604/pamj.2017.27.153.10915 http://scihub22266oqcxt.onion/10.11604/pamj.2017.27.153.10915 C5567971!5567971 !28904681     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28904681 &cmd=llinks): Failed to open stream: HTTP request failed! 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Clinicopathological findings and outcome of lupus nephritis in Tunisian children: a review of 43 patients |pdf=|usr=}}{{28904681 }} gab.com Text Clinicopathological findings and outcome of lupus nephritis in Tunisian children: a review of 43 patients JO: Pan Afr Med J http://www.kidney.de/pget.php?&tw=1&pmid=28904681 #FOAvip We report clinical and renal histological data, treatment modalities and outcome of 43 Tunisian children with biopsy-proven lupus nephritis seen over a 23-year period. There were 39 girls and 4 boys with a mean age of 12.5 years at diagnosis of lupus nephritis and followed for a mean period of 77 months. Renal symptoms included urinary abnormalities in all patients, hypertension in 40% of cases, nephrotic syndrome in 60% of cases and renal failure in 25% of cases. Class IV and class III nephritis were observed in 48.8 % and 30.2 % respectively. Corticosteroids were used in all cases, associated to immunosuppressive therapy in 23%. Overall survival was 86% at 5 years and 74% at 10 and 15 years. Renal survival was 83% at 5 and 10 years and 63% at 15 years. Initial renal failure and tubulointerstitial fibrosis were significantly increased risk for the development of end-stage renal disease in our study group. Renal histological findings provide the basis for treatment recommendations. Timely performed renal biopsy is greatly needed to accurately determine the prognosis and to guide treatment in children lupus nephritis. Twit Text FOAVip Clinicopathological findings and outcome of lupus nephritis in Tunisian children: a review of 43 patients ????Pan Afr Med J http://www.kidney.de/pget.php?&tw=1&pmid=28904681 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28904681 #FOAvip English Wikipedia <ref>{{Cite pmid|28904681 }}</ref> Clinicopathological findings and outcome of lupus nephritis in Tunisian children: a review of 43 patients #MMPMID28904681 Jebali H ; Hajji M ; Rais L ; Hamida FB ; Beji S ; Zouaghi MK Pan Afr Med J 2017[]; 27 (ä): 153 PMID28904681 show ga We report clinical and renal histological data, treatment modalities and outcome of 43 Tunisian children with biopsy-proven lupus nephritis seen over a 23-year period. There were 39 girls and 4 boys with a mean age of 12.5 years at diagnosis of lupus nephritis and followed for a mean period of 77 months. Renal symptoms included urinary abnormalities in all patients, hypertension in 40% of cases, nephrotic syndrome in 60% of cases and renal failure in 25% of cases. Class IV and class III nephritis were observed in 48.8 % and 30.2 % respectively. Corticosteroids were used in all cases, associated to immunosuppressive therapy in 23%. Overall survival was 86% at 5 years and 74% at 10 and 15 years. Renal survival was 83% at 5 and 10 years and 63% at 15 years. Initial renal failure and tubulointerstitial fibrosis were significantly increased risk for the development of end-stage renal disease in our study group. Renal histological findings provide the basis for treatment recommendations. Timely performed renal biopsy is greatly needed to accurately determine the prognosis and to guide treatment in children lupus nephritis. |Adolescent [MESH] |Biopsy [MESH] |Child [MESH] |Child, Preschool [MESH] |Female [MESH] |Glucocorticoids/therapeutic use [MESH] |Humans [MESH] |Hypertension/epidemiology/*etiology [MESH] |Immunosuppressive Agents/therapeutic use [MESH] |Kidney Failure, Chronic/epidemiology/*etiology [MESH] |Lupus Nephritis/complications/drug therapy/*physiopathology [MESH] |Male [MESH] |Nephrotic Syndrome/epidemiology/*etiology [MESH] |Prognosis [MESH] |Renal Insufficiency/epidemiology/etiology [MESH] |Retrospective Studies [MESH] |Survival Rate [MESH] |Time Factors [MESH] |Tunisia [MESH]Clinicopathological findings and outcome of lupus nephritis in Tunisia(epmc).pdf DeepDyve Pubget Overpricing