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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Dent+Anesth+Pain+Med
2016 ; 16
(1
): 25-29
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gab.com Text
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English Wikipedia
Intranasal administration of dexmedetomidine (DEX) as a premedication for
pediatric patients undergoing general anesthesia for dental treatment
#MMPMID28879292
Lee Y
; Kim J
; Kim S
; Kim J
J Dent Anesth Pain Med
2016[Mar]; 16
(1
): 25-29
PMID28879292
show ga
BACKGROUND: The most important reason for pre-operative administration of
medication is to reduce anxiety. Alleviation of fear and anxiety about surgery
enables patients to remain comfortable during treatment. Dexmedetomidine (DEX) is
a fast-acting drug that is used as a premedication in different circumstances
because it has sedative and anti-anxiolytic effects, and stable hemodynamics. It
also has the advantage of intranasal administration. The aim of this study was to
investigate the effects and hemodynamic stability of DEX by retrospectively
analyzing cases in which DEX was administered nasally as a premedication.
METHODS: Ten patients treated at Dankook University Dental Hospital, recruited
between February and April 2015, received intranasal delivery of 2 µg/kg DEX, 30
minutes prior to general anesthesia. Anesthesia records of anxiety, blood
pressure, respiration, pulse, estimated arterial oxygen saturation (SpO(2)), and
partial pressure, or maximum concentration, of carbon dioxide (ETCO(2)) were
analyzed. RESULTS: Administration of DEX prior to a general anesthetic
effectively relieved anxiety. Respiratory depression, the most severe adverse
effect of other sedatives, was not observed. Hemodynamic stability under general
anesthesia was maintained during treatment and a reduction in emergence delirium
was observed upon completion of treatment. CONCLUSIONS: Premedication
administration of DEX is safe for pediatric patients undergoing dental treatment
under general anesthesia.