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10.1016/j.jacc.2017.05.034 http://scihub22266oqcxt.onion/10.1016/j.jacc.2017.05.034 C5551687!5551687!28683968     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Am+Coll+Cardiol 2017 ; 70 (2): 196-211 Nephropedia Template TP {{tp|p=28683968|t=2017. Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of 3-Part Series |pdf=|usr=}}{{28683968}} gab.com Text Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of 3-Part Series JO: J Am Coll Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28683968 #FOAvip The generation of reactive oxygen species (ROS) is a fundamental aspect of normal human biology. However, when ROS generation exceeds endogenous antioxidant capacity, oxidative stress arises. If unchecked, ROS production and oxidative stress mediate tissue and cell damage that can spiral in a cycle of inflammation and more oxidative stress. This article is Part 1 of a 3-part series covering The Role of Oxidative Stress in Cardiovascular Disease. The broad theme of this first paper is the mechanisms and biology of oxidative stress. Specifically, we review the basic biology of oxidative stress, relevant aspects of mitochondrial function, and stress-related cell death pathways (apoptosis and necrosis) as they relate to the heart and cardiovascular system. We then explore telomere biology and cell senescence. As important regulators and sensors of oxidative stress, telomeres are segments of repetitive nucleotide sequence at each end of a chromosome that protect the chromosome ends from deterioration. Twit Text FOAVip Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of 3-Part Series ????J Am Coll Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28683968 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28683968 #FOAvip English Wikipedia <ref>{{Cite pmid|28683968}}</ref> Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of 3-Part Series #MMPMID28683968 Sack MN; Fyhrquist FY; Saijonmaa OJ; Fuster V; Kovacic JC J Am Coll Cardiol 2017[Jul]; 70 (2): 196-211 PMID28683968show ga The generation of reactive oxygen species (ROS) is a fundamental aspect of normal human biology. However, when ROS generation exceeds endogenous antioxidant capacity, oxidative stress arises. If unchecked, ROS production and oxidative stress mediate tissue and cell damage that can spiral in a cycle of inflammation and more oxidative stress. This article is Part 1 of a 3-part series covering The Role of Oxidative Stress in Cardiovascular Disease. The broad theme of this first paper is the mechanisms and biology of oxidative stress. Specifically, we review the basic biology of oxidative stress, relevant aspects of mitochondrial function, and stress-related cell death pathways (apoptosis and necrosis) as they relate to the heart and cardiovascular system. We then explore telomere biology and cell senescence. As important regulators and sensors of oxidative stress, telomeres are segments of repetitive nucleotide sequence at each end of a chromosome that protect the chromosome ends from deterioration. äBasic Biology of Oxidative Stress and the Cardiovascular System: Part (epmc).pdf DeepDyve Pubget Overpricing