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10.1097/ACI.0000000000000341 http://scihub22266oqcxt.onion/10.1097/ACI.0000000000000341 C5550831!5550831!28092287     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28092287&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Allergy+Clin+Immunol 2017 ; 17 (2): 146-52 Nephropedia Template TP {{tp|p=28092287|t=2017. Current and Future Management of the Young Child with Early Onset Wheezing |pdf=|usr=}}{{28092287}} gab.com Text Current and Future Management of the Young Child with Early Onset Wheezing JO: Curr Opin Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28092287 #FOAvip Purpose of Review: In this review, we discuss current thinking in relation to available guidelines for the care of preschool-aged children with recurrent wheezing, while highlighting the gaps in our knowledge and discussing changes that could occur over the next 5 years. Recent Findings: The Asthma Predictive Index (API) as well as allergen-specific IgE, peripheral eosinophil count, and exhaled nitric oxide are perhaps under-utilized sources of information that can assist in predicting progression to asthma and response to therapies. Inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRA) decrease impairment and exacerbation frequency in wheezing children but are not disease modifying. Macrolides may be useful during acute wheezing episodes for preventing progression to more severe symptoms. Monoclonal antibodies targeting IgE and TH2 cytokines have been successful in trials of adults and older children with asthma, but trials in younger children are needed. Summary: Establishing the phenotype and endotype of young wheezing children can be useful for prognostication of future asthma risk as well as for selection of the most appropriate treatment. Primary asthma prevention strategies are needed during the critical developmental window in early life prior to the onset of irrecoverable loss of lung function. Twit Text FOAVip Current and Future Management of the Young Child with Early Onset Wheezing ????Curr Opin Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28092287 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28092287 #FOAvip English Wikipedia <ref>{{Cite pmid|28092287}}</ref> Current and Future Management of the Young Child with Early Onset Wheezing #MMPMID28092287 Burbank AJ; Szefler SJ Curr Opin Allergy Clin Immunol 2017[Apr]; 17 (2): 146-52 PMID28092287show ga Purpose of Review: In this review, we discuss current thinking in relation to available guidelines for the care of preschool-aged children with recurrent wheezing, while highlighting the gaps in our knowledge and discussing changes that could occur over the next 5 years. Recent Findings: The Asthma Predictive Index (API) as well as allergen-specific IgE, peripheral eosinophil count, and exhaled nitric oxide are perhaps under-utilized sources of information that can assist in predicting progression to asthma and response to therapies. Inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRA) decrease impairment and exacerbation frequency in wheezing children but are not disease modifying. Macrolides may be useful during acute wheezing episodes for preventing progression to more severe symptoms. Monoclonal antibodies targeting IgE and TH2 cytokines have been successful in trials of adults and older children with asthma, but trials in younger children are needed. Summary: Establishing the phenotype and endotype of young wheezing children can be useful for prognostication of future asthma risk as well as for selection of the most appropriate treatment. Primary asthma prevention strategies are needed during the critical developmental window in early life prior to the onset of irrecoverable loss of lung function. äCurrent and Future Management of the Young Child with Early Onset Whee(epmc).pdf DeepDyve Pubget Overpricing