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10.1177/1073858417691030 http://scihub22266oqcxt.onion/10.1177/1073858417691030 C5547012!5547012!28466758     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Neuroscientist 2017 ; 23 (5): 454-65 Nephropedia Template TP {{tp|p=28466758|t=2017. The Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal Fluid Transport |pdf=|usr=}}{{28466758}} gab.com Text The Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal Fluid Transport JO: Neuroscientist http://www.kidney.de/pget.php?&tw=1&pmid=28466758 #FOAvip The overall premise of this review is that cerebrospinal fluid (CSF) is transported within a dedicated peri-vascular network facilitating metabolic waste clearance from the central nervous system while we sleep. The anatomical profile of the network is complex and has been defined as a peri-arterial CSF influx pathway and peri-venous clearance routes, which are functionally coupled by interstitial bulk flow supported by astrocytic aquaporin 4 water channels. The role of the newly discovered system in the brain is equivalent to the lymphatic system present in other body organs and has been termed the ?glymphatic pathway? or ?(g)lymphatics? because of its dependence on glial cells. We will discuss and review the general anatomy and physiology of CSF from the perspective of the glymphatic pathway, a discovery which has greatly improved our understanding of key factors that control removal of metabolic waste products from the central nervous system in health and disease and identifies an additional purpose for sleep. A brief historical and factual description of CSF production and transport will precede the ensuing discussion of the glymphatic system along with a discussion of its clinical implications. Twit Text FOAVip The Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal Fluid Transport ????Neuroscientist http://www.kidney.de/pget.php?&tw=1&pmid=28466758 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28466758 #FOAvip English Wikipedia <ref>{{Cite pmid|28466758}}</ref> The Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal Fluid Transport #MMPMID28466758 Benveniste H; Lee H; Volkow ND Neuroscientist 2017[Oct]; 23 (5): 454-65 PMID28466758show ga The overall premise of this review is that cerebrospinal fluid (CSF) is transported within a dedicated peri-vascular network facilitating metabolic waste clearance from the central nervous system while we sleep. The anatomical profile of the network is complex and has been defined as a peri-arterial CSF influx pathway and peri-venous clearance routes, which are functionally coupled by interstitial bulk flow supported by astrocytic aquaporin 4 water channels. The role of the newly discovered system in the brain is equivalent to the lymphatic system present in other body organs and has been termed the ?glymphatic pathway? or ?(g)lymphatics? because of its dependence on glial cells. We will discuss and review the general anatomy and physiology of CSF from the perspective of the glymphatic pathway, a discovery which has greatly improved our understanding of key factors that control removal of metabolic waste products from the central nervous system in health and disease and identifies an additional purpose for sleep. A brief historical and factual description of CSF production and transport will precede the ensuing discussion of the glymphatic system along with a discussion of its clinical implications. äThe Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal F(epmc).pdf DeepDyve Pubget Overpricing