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2017 ; 13
(7
): 1239-1240
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English Wikipedia
Vacuolar digestion of entire damaged chloroplasts in Arabidopsis thaliana is
accomplished by chlorophagy
#MMPMID28548870
Izumi M
; Nakamura S
Autophagy
2017[Jul]; 13
(7
): 1239-1240
PMID28548870
show ga
In yeast and mammals, selective vacuolar delivery and degradation of whole
mitochondria, or mitophagy, represents an important quality control system and is
achieved by a cargo recognition mechanism enabling selective elimination of
dysfunctional mitochondria. As photosynthetic organelles that need light for
energy production, plant chloroplasts accumulate sunlight-induced damage. Plants
have evolved multiple mechanisms to avoid, relieve, or repair chloroplast
photodamage. Our recent study showed that vacuolar degradation of entire
chloroplasts, termed chlorophagy, is induced to degrade chloroplasts that are
collapsed due to photodamage. Our results underscore the involvement of autophagy
in the quality control of endosymbiotic, energy-converting organelles in
eukaryotes.