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10.1080/15548627.2017.1313946 http://scihub22266oqcxt.onion/10.1080/15548627.2017.1313946 C5529073!5529073!28486053     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Autophagy 2017 ; 13 (7): 1248-9 Nephropedia Template TP {{tp|p=28486053|t=2017. Active Interaction Mapping as a tool to elucidate hierarchical functions of biological processes |pdf=|usr=}}{{28486053}} gab.com Text Active Interaction Mapping as a tool to elucidate hierarchical functions of biological processes JO: Autophagy http://www.kidney.de/pget.php?&tw=1&pmid=28486053 #FOAvip Increasingly, various ?omics data are contributing significantly to our understanding of novel biological processes, but it has not been possible to iteratively elucidate hierarchical functions in complex phenomena. We describe a general systems biology approach called Active Interaction Mapping (AI-MAP), which elucidates the hierarchy of functions for any biological process. Existing and new ?omics data sets can be iteratively added to create and improve hierarchical models which enhance our understanding of particular biological processes. The best datatypes to further improve an AI-MAP model are predicted computationally. We applied this approach to our understanding of general and selective autophagy, which are conserved in most eukaryotes, setting the stage for the broader application to other cellular processes of interest. In the particular application to autophagy-related processes, we uncovered and validated new autophagy and autophagy-related processes, expanded known autophagy processes with new components, integrated known non-autophagic processes with autophagy and predict other unexplored connections. Twit Text FOAVip Active Interaction Mapping as a tool to elucidate hierarchical functions of biological processes ????Autophagy http://www.kidney.de/pget.php?&tw=1&pmid=28486053 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28486053 #FOAvip English Wikipedia <ref>{{Cite pmid|28486053}}</ref> Active Interaction Mapping as a tool to elucidate hierarchical functions of biological processes #MMPMID28486053 Farré JC; Kramer M; Ideker T; Subramani S Autophagy 2017[]; 13 (7): 1248-9 PMID28486053show ga Increasingly, various ?omics data are contributing significantly to our understanding of novel biological processes, but it has not been possible to iteratively elucidate hierarchical functions in complex phenomena. We describe a general systems biology approach called Active Interaction Mapping (AI-MAP), which elucidates the hierarchy of functions for any biological process. Existing and new ?omics data sets can be iteratively added to create and improve hierarchical models which enhance our understanding of particular biological processes. The best datatypes to further improve an AI-MAP model are predicted computationally. We applied this approach to our understanding of general and selective autophagy, which are conserved in most eukaryotes, setting the stage for the broader application to other cellular processes of interest. In the particular application to autophagy-related processes, we uncovered and validated new autophagy and autophagy-related processes, expanded known autophagy processes with new components, integrated known non-autophagic processes with autophagy and predict other unexplored connections. äActive Interaction Mapping as a tool to elucidate hierarchical functio(epmc).pdf DeepDyve Pubget Overpricing