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10.1038/aps.2017.12 http://scihub22266oqcxt.onion/10.1038/aps.2017.12 C5520184!5520184!28392567     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Pharmacol+Sin 2017 ; 38 (6): 754-63 Nephropedia Template TP {{tp|p=28392567|t=2017. Engineering exosomes as refined biological nanoplatforms for drug delivery |pdf=|usr=}}{{28392567}} gab.com Text Engineering exosomes as refined biological nanoplatforms for drug delivery JO: Acta Pharmacol Sin http://www.kidney.de/pget.php?&tw=1&pmid=28392567 #FOAvip Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important mediators of long distance intercellular communication and are involved in a diverse range of biological processes. Because of their ideal native structure and characteristics, exosomes are promising nanocarriers for clinical use. Exosomes are engineered at the cellular level under natural conditions, but successful exosome modification requires further exploration. The focus of this paper is to summarize passive and active loading approaches, as well as specific exosome modifications and examples of the delivery of therapeutic and imaging molecules. Examples of exosomes derived from a variety of biological origins are also provided. The biocompatible characteristics of exosomes, with suitable modifications, can increase the stability and efficacy of imaging probes and therapeutics while enhancing cellular uptake. Challenges in clinical translation of exosome-based platforms from different cell sources and the advantages of each are also reviewed and discussed. Twit Text FOAVip Engineering exosomes as refined biological nanoplatforms for drug delivery ????Acta Pharmacol Sin http://www.kidney.de/pget.php?&tw=1&pmid=28392567 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28392567 #FOAvip English Wikipedia <ref>{{Cite pmid|28392567}}</ref> Engineering exosomes as refined biological nanoplatforms for drug delivery #MMPMID28392567 Luan X; Sansanaphongpricha K; Myers I; Chen H; Yuan H; Sun D Acta Pharmacol Sin 2017[Jun]; 38 (6): 754-63 PMID28392567show ga Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important mediators of long distance intercellular communication and are involved in a diverse range of biological processes. Because of their ideal native structure and characteristics, exosomes are promising nanocarriers for clinical use. Exosomes are engineered at the cellular level under natural conditions, but successful exosome modification requires further exploration. The focus of this paper is to summarize passive and active loading approaches, as well as specific exosome modifications and examples of the delivery of therapeutic and imaging molecules. Examples of exosomes derived from a variety of biological origins are also provided. The biocompatible characteristics of exosomes, with suitable modifications, can increase the stability and efficacy of imaging probes and therapeutics while enhancing cellular uptake. Challenges in clinical translation of exosome-based platforms from different cell sources and the advantages of each are also reviewed and discussed. äEngineering exosomes as refined biological nanoplatforms for drug deli(epmc).pdf DeepDyve Pubget Overpricing