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10.2169/internalmedicine.56.7908

http://scihub22266oqcxt.onion/10.2169/internalmedicine.56.7908
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suck abstract from ncbi


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pmid28674357
      Intern+Med 2017 ; 56 (13 ): 1679-1686
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  • Single-dose Rituximab Therapy for Refractory Idiopathic Membranous Nephropathy: A Single-center Experience #MMPMID28674357
  • Katsuno T ; Ozaki T ; Kim H ; Kato N ; Suzuki Y ; Akiyama S ; Ishimoto T ; Kosugi T ; Tsuboi N ; Ito Y ; Maruyama S
  • Intern Med 2017[]; 56 (13 ): 1679-1686 PMID28674357 show ga
  • To date, a recognized treatment for refractory membranous nephropathy (MN) has not been established. Recently, several reports have indicated the efficacy of rituximab as a novel treatment option. However, only a few published accounts exist of rituximab therapy for idiopathic MN (IMN) in the Asian population. We present the cases of three IMN patients who were treated with single-dose rituximab after they showed no response to conventional therapies, including corticosteroids, cyclosporine, cyclophosphamide, mizoribine, and mycophenolate mofetil. Although one case showed no response, a complete or incomplete remission was achieved in the other two cases. Rituximab may therefore be a beneficial treatment option for IMN.
  • |Adrenal Cortex Hormones/therapeutic use [MESH]
  • |Adult [MESH]
  • |Aged [MESH]
  • |Asian People [MESH]
  • |Cyclophosphamide/therapeutic use [MESH]
  • |Cyclosporine/therapeutic use [MESH]
  • |Glomerulonephritis, Membranous/*drug therapy [MESH]
  • |Glucocorticoids/therapeutic use [MESH]
  • |Humans [MESH]
  • |Immunosuppressive Agents/administration & dosage/*therapeutic use [MESH]
  • |Male [MESH]
  • |Mycophenolic Acid/therapeutic use [MESH]
  • |Ribonucleosides/therapeutic use [MESH]


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