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2017 ; 10
(1
): 28-36
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Prevalence of periodontal pathogens among italian patients with chronic
periodontitis: a retrospective study on 2992 patients
#MMPMID28757933
Tettamanti L
; Gaudio RM
; Cura F
; Mucchi D
; Illuzzi N
; Tagliabue A
Oral Implantol (Rome)
2017[Jan]; 10
(1
): 28-36
PMID28757933
show ga
PURPOSE: The aim of the present study was to evaluate the prevalence of some
periodontal pathogens in Italian adults with chronic periodontitis. MATERIALS AND
METHODS: The sample consisted of 2992 patients with a clinical diagnosis of
chronic periodontitis, based on the criteria of the American Academy of
Periodontology, sampled in the period 2013-2016: 2108 patients were from
Northern, 690 from Central and 194 from Southern Italy. Porphyromonas gengivalis,
Treponema denticola, and Tannerella forsythia were investigated in all patients
of the present study, while Campylobacter rectus, Fusobacterium nucleatum and
Aggregatibacter actinomycetemcomitans only in 2514 (84%) patients. Subgingival
plaque samples of the four sites of greatest probing depth in each patient were
used to obtain subgingival microbiota and then processed by quantitative
polymerase chain reaction. RESULTS: Periodontal pathogens had the following
presence respect to all amount of patients: Aggregatibacter actinomycetemcomitans
16.1%, Campylobacter rectus 73.4%, Fusobacterium nucleatum 93.8%, Porphyromonas
gengivalis 65.5%, Treponema denticola 66.4%, and Tannerella forsythia 72.7%.
There are no significant statistical differences among geographic areas both for
the total bacterial and the single species except for T. Denticola and C. Rectus,
which prevalence was significantly higher in Southern Italy (P value <.05). The
other investigated species were equally distributed among different regions. A.
actinomycetemcomitans was the rarer species detected in this study, while F.
nucleatum was the commonest. No differences among areas where observed as regard
of the mean bacterial load except for F. Nucleatum whose prevalence in Northern
Italy was lower then both in Central and Southern Italy (P value <.05).
CONCLUSIONS: The results of our study didn't show different geographic
distribution of periodontal pathogens among Italian population of the three areas
investigated. The homogeneity of the results could be related to genetic and
environmental factors.