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10.1186/s13073-017-0460-y

http://scihub22266oqcxt.onion/10.1186/s13073-017-0460-y
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C5516356!5516356 !28720124
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suck abstract from ncbi

pmid28720124
      Genome+Med 2017 ; 9 (1 ): 66
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  • Defining the role of Lgr5(+) stem cells in colorectal cancer: from basic research to clinical applications #MMPMID28720124
  • Fujii M ; Sato T
  • Genome Med 2017[Jul]; 9 (1 ): 66 PMID28720124 show ga
  • Intestinal epithelium is structured by two distinct components: the villi and the crypts. The crypts harbor stem cells expressing Lgr5 and thus have been a representative model to study tissue stem cell functions. Recent advances in organoid technology and analytical modalities have enabled precise characterization of Lgr5(+) intestinal stem cells, providing insights into their roles in homeostasis and cancer.
  • |*Receptors, G-Protein-Coupled [MESH]
  • |Animals [MESH]
  • |Colorectal Neoplasms/*metabolism [MESH]
  • |Humans [MESH]
  • |Intestinal Mucosa/*cytology [MESH]


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