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10.1186/s12882-017-0648-9 http://scihub22266oqcxt.onion/10.1186/s12882-017-0648-9 C5512990!5512990 !28709416     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28709416 &cmd=llinks): Failed to open stream: HTTP request failed! 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Warfarin-induced toxic epidermal necrolysis in combination therapy of Henoch-Schönlein purpura nephritis: a case report |pdf=|usr=}}{{28709416 }} gab.com Text Warfarin-induced toxic epidermal necrolysis in combination therapy of Henoch-Schönlein purpura nephritis: a case report JO: BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28709416 #FOAvip BACKGROUND: Toxic epidermal necrolysis (TEN) is a rare life-threatening condition almost exclusively attributed to drugs. The main etiologic factors for TEN are sulphonamides, anticonvulsants, and antibiotics; however, there are no published reports of warfarin causing TEN. CASE PRESENTATION: We present the case of a 3-year-old patient who developed TEN while receiving treatment for Henoch-Schönlein purpura nephritis (HSPN). With multiple-drug therapy comprising prednisolone, mizoribine, dipyridamole, and warfarin, it is difficult to detect which drug is the causative agent. While in most cases, diagnosis of the causative drug is based on clinical history without a lymphocyte transformation test (LTT), we performed the test three times and identified the causative drug as warfarin at the late phase. We continued HSPN treatment without warfarin, and results showed good renal function without life-threatening complications. CONCLUSION: To our knowledge, this is the first report about TEN caused by warfarin. Repeated LTTs could be useful for identifying TEN-causative drugs even in the late phase. Twit Text FOAVip Warfarin-induced toxic epidermal necrolysis in combination therapy of Henoch-Schönlein purpura nephritis: a case report ????BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28709416 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28709416 #FOAvip English Wikipedia <ref>{{Cite pmid|28709416 }}</ref> Warfarin-induced toxic epidermal necrolysis in combination therapy of Henoch-Schönlein purpura nephritis: a case report #MMPMID28709416 Kasahara K ; Gotoh Y ; Kuroyanagi Y ; Nagano C BMC Nephrol 2017[Jul]; 18 (1 ): 237 PMID28709416 show ga BACKGROUND: Toxic epidermal necrolysis (TEN) is a rare life-threatening condition almost exclusively attributed to drugs. The main etiologic factors for TEN are sulphonamides, anticonvulsants, and antibiotics; however, there are no published reports of warfarin causing TEN. CASE PRESENTATION: We present the case of a 3-year-old patient who developed TEN while receiving treatment for Henoch-Schönlein purpura nephritis (HSPN). With multiple-drug therapy comprising prednisolone, mizoribine, dipyridamole, and warfarin, it is difficult to detect which drug is the causative agent. While in most cases, diagnosis of the causative drug is based on clinical history without a lymphocyte transformation test (LTT), we performed the test three times and identified the causative drug as warfarin at the late phase. We continued HSPN treatment without warfarin, and results showed good renal function without life-threatening complications. CONCLUSION: To our knowledge, this is the first report about TEN caused by warfarin. Repeated LTTs could be useful for identifying TEN-causative drugs even in the late phase. |Anticoagulants/administration & dosage/*adverse effects [MESH] |Child, Preschool [MESH] |Combined Modality Therapy/adverse effects [MESH] |Drug Therapy, Combination [MESH] |Female [MESH] |Humans [MESH] |IgA Vasculitis/*chemically induced/complications/*diagnosis [MESH] |Methylprednisolone/administration & dosage/adverse effects [MESH] |Stevens-Johnson Syndrome/complications/*diagnosis [MESH]Warfarin-induced toxic epidermal necrolysis in combination therapy of (epmc).pdf DeepDyve Pubget Overpricing