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10.4172/2476-1966.1000122 http://scihub22266oqcxt.onion/10.4172/2476-1966.1000122 C5512601!5512601!28725880     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunobiol 2017 ; 2 (2): ä Nephropedia Template TP {{tp|p=28725880|t=2017. Role of Intrinsic Factors in the Growth of Transplanted Organs Following Transplantation |pdf=|usr=}}{{28725880}} gab.com Text Role of Intrinsic Factors in the Growth of Transplanted Organs Following Transplantation JO: J Immunobiol http://www.kidney.de/pget.php?&tw=1&pmid=28725880 #FOAvip Shortages in the availability of transplantable organs have forced the transplant community to seek alternative methods to increase the supply of available organs. In our recent study following ?-1,3-galactocyltransferase knockout (GalT-KO) pig-to-baboon kidney xenotransplantation, we found that certain recipients developed increased serum creatinine, possibly due to the rapid growth of orthotopic pig grafts in smaller baboon recipients. To test our hypothesis, we assessed whether the growth of outbred (Yorkshire) organ transplants (kidney and lung) in miniature swine was regulated by intrinsic (graft) factors. Yorkshire kidneys reached 3.7× their initial volume over 3 months vs. 1.2× for miniature swine kidneys over a similar time period. A similar pattern was seen in porcine lung allografts as well. Following xenotransplantation, a review of our results suggests that there is a threshold for kidney graft volume of 25 cm3/kg of recipient body weight at which cortical ischemia is induced in transplanted GalT-KO kidneys in baboons. These results suggest that intrinsic factors are in part responsible for the growth of donor organs and this should be taken into consideration for growth-curve-mismatched transplants. Twit Text FOAVip Role of Intrinsic Factors in the Growth of Transplanted Organs Following Transplantation ????J Immunobiol http://www.kidney.de/pget.php?&tw=1&pmid=28725880 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28725880 #FOAvip English Wikipedia <ref>{{Cite pmid|28725880}}</ref> Role of Intrinsic Factors in the Growth of Transplanted Organs Following Transplantation #MMPMID28725880 Shah JA; Tanabe T; Yamada K J Immunobiol 2017[Jun]; 2 (2): ä PMID28725880show ga Shortages in the availability of transplantable organs have forced the transplant community to seek alternative methods to increase the supply of available organs. In our recent study following ?-1,3-galactocyltransferase knockout (GalT-KO) pig-to-baboon kidney xenotransplantation, we found that certain recipients developed increased serum creatinine, possibly due to the rapid growth of orthotopic pig grafts in smaller baboon recipients. To test our hypothesis, we assessed whether the growth of outbred (Yorkshire) organ transplants (kidney and lung) in miniature swine was regulated by intrinsic (graft) factors. Yorkshire kidneys reached 3.7× their initial volume over 3 months vs. 1.2× for miniature swine kidneys over a similar time period. A similar pattern was seen in porcine lung allografts as well. Following xenotransplantation, a review of our results suggests that there is a threshold for kidney graft volume of 25 cm3/kg of recipient body weight at which cortical ischemia is induced in transplanted GalT-KO kidneys in baboons. These results suggest that intrinsic factors are in part responsible for the growth of donor organs and this should be taken into consideration for growth-curve-mismatched transplants. äRole of Intrinsic Factors in the Growth of Transplanted Organs Followi(epmc).pdf DeepDyve Pubget Overpricing