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10.1016/j.jare.2017.04.006

http://scihub22266oqcxt.onion/10.1016/j.jare.2017.04.006
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suck abstract from ncbi


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pmid28748121
      J+Adv+Res 2017 ; 8 (5 ): 551-554
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  • Treatment of asymptomatic hyperuricemia in chronic kidney disease: A new target in an old enemy - A review #MMPMID28748121
  • Ramirez MEG ; Bargman JM
  • J Adv Res 2017[Sep]; 8 (5 ): 551-554 PMID28748121 show ga
  • Asymptomatic hyperuricemia is increasing in prevalence. There is a growing body of literature suggesting that uric acid has deleterious effects on vascular health and renal histological integrity. Several trials, reviewed herein, suggest that lowering the serum uric acid level is associated with a slowing in the rate of renal deterioration in those with chronic kidney disease. Given that there is little available in the general armamentarium to slow the rate of kidney deterioration, strong consideration could be given to the administration of agents or lifestyle changes that decrease uric acid production in hyperuricemic patients with deteriorating kidney function.
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