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10.1146/annurev-immunol-041015-055254 http://scihub22266oqcxt.onion/10.1146/annurev-immunol-041015-055254 C5508990!5508990 !28125356     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28125356 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Annu+Rev+Immunol 2017 ; 35 (?): 149-176 Nephropedia Template TP {{tp|p=28125356 |t=2017. The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules |pdf=|usr=}}{{28125356 }} gab.com Text The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules JO: Annu Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28125356 #FOAvip To monitor the health of cells, the immune system tasks antigen-presenting cells with gathering antigens from other cells and bringing them to CD8 T cells in the form of peptides bound to MHC-I molecules. Most cells would be unable to perform this function because they use their MHC-I molecules to exclusively present peptides derived from the cell's own proteins. However, the immune system evolved mechanisms for dendritic cells and some other phagocytes to sample and present antigens from the extracellular milieu on MHC-I through a process called cross-presentation. How this important task is accomplished, its role in health and disease, and its potential for exploitation are the subject of this review. Twit Text FOAVip The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules ????Annu Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28125356 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28125356 #FOAvip English Wikipedia <ref>{{Cite pmid|28125356 }}</ref> The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules #MMPMID28125356 Cruz FM ; Colbert JD ; Merino E ; Kriegsman BA ; Rock KL Annu Rev Immunol 2017[Apr]; 35 (?): 149-176 PMID28125356 show ga To monitor the health of cells, the immune system tasks antigen-presenting cells with gathering antigens from other cells and bringing them to CD8 T cells in the form of peptides bound to MHC-I molecules. Most cells would be unable to perform this function because they use their MHC-I molecules to exclusively present peptides derived from the cell's own proteins. However, the immune system evolved mechanisms for dendritic cells and some other phagocytes to sample and present antigens from the extracellular milieu on MHC-I through a process called cross-presentation. How this important task is accomplished, its role in health and disease, and its potential for exploitation are the subject of this review. |*Cross-Priming [MESH] |Animals [MESH] |Antigens/immunology/metabolism [MESH] |CD8-Positive T-Lymphocytes/*immunology [MESH] |Dendritic Cells/*immunology [MESH] |Histocompatibility Antigens Class I/metabolism [MESH] |Humans [MESH] |Immunologic Surveillance [MESH] |Lymphocyte Activation [MESH]The Biology and Underlying Mechanisms of Cross-Presentation of Exogeno(epmc).pdf DeepDyve Pubget Overpricing