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10.1364/BOE.8.003248

http://scihub22266oqcxt.onion/10.1364/BOE.8.003248
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suck abstract from ncbi


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pmid28717565
      Biomed+Opt+Express 2017 ; 8 (7 ): 3248-3280
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  • Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT Invited #MMPMID28717565
  • de Boer JF ; Leitgeb R ; Wojtkowski M
  • Biomed Opt Express 2017[Jul]; 8 (7 ): 3248-3280 PMID28717565 show ga
  • Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of non-invasive and non-contact imaging by detecting back-scattered light. OCT has gone through a tremendous development over the past 25 years. From its initial inception in 1991 [Science254, 1178 (1991)] it has become an indispensable medical imaging technology in ophthalmology. Also in fields like cardiology and gastro-enterology the technology is envisioned to become a standard of care. A key contributor to the success of OCT has been the sensitivity and speed advantage offered by Fourier domain OCT. In this review paper the development of FD-OCT will be revisited, providing a single comprehensive framework to derive the sensitivity advantage of both SD- and SS-OCT. We point out the key aspects of the physics and the technology that has enabled a more than 2 orders of magnitude increase in sensitivity, and as a consequence an increase in the imaging speed without loss of image quality. This speed increase provided a paradigm shift from point sampling to comprehensive 3D in vivo imaging, whose clinical impact is still actively explored by a large number of researchers worldwide.
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