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10.1111/bdi.12416 http://scihub22266oqcxt.onion/10.1111/bdi.12416 C5508736!5508736!27425597     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bipolar+Disord 2016 ; 18 (5): 404-9 Nephropedia Template TP {{tp|p=27425597|t=2016. Individuals Hospitalized with Acute Mania Have Increased Exposure to Antimicrobial Medications |pdf=|usr=}}{{27425597}} gab.com Text Individuals Hospitalized with Acute Mania Have Increased Exposure to Antimicrobial Medications JO: Bipolar Disord http://www.kidney.de/pget.php?&tw=1&pmid=27425597 #FOAvip Objectives: We have preciously documented that many individuals with acute mania have immune activation. However the sources of immune activation have not been identified. We investigated whether individuals hospitalized with acute mania have evidence of bacterial infections as determined by the prescription of systemic antimicrobial agents. Methods: We assessed the recent prescription of systemic antimicrobial medications and the site of presumed bacterial infection in 234 individuals hospitalized for acute mania in either an inpatient unit or a day hospital. We also assessed individuals hospitalized for other psychiatric disorders (N=368) and controls (N=555). We employed logistic regression models to compare the rates of antibiotic prescription in individuals with the different diagnoses employing demographic variables as covariates. Results: We found that individuals hospitalized with acute mania had a substantially increased rate of recent antimicrobial prescription defined as exposure within 3 days of ascertainment (Adjusted Odds Ratio 5.5, 95% CI 2.2, 14.1, p<.0002). Overall a total of 18 of the 234 (7.7%)% of individuals hospitalized for acute mania were prescribed antibiotics as opposed to 7 of 555 (1.3%) controls. The prescription of antibiotics was associated with being in an inpatient unit as opposed to being in the day hospital and having increased mania symptom severity but not with other clinical ratings, demographic variables, or psychiatric medications. Hospitalization for other psychiatric disorders was not associated with the recent prescription of antimicrobial medications. The urinary tract was the most common site of infection in women while the respiratory tract and mucosal surfaces were the most common sites in men. Conclusion: Individuals hospitalized with acute mania have a markedly increased rate of bacterial infections as evidenced by the recent prescription of antimicrobial agents. The prevention and effective treatment of bacterial infections may be important interventions for the management of individuals with mania. Twit Text FOAVip Individuals Hospitalized with Acute Mania Have Increased Exposure to Antimicrobial Medications ????Bipolar Disord http://www.kidney.de/pget.php?&tw=1&pmid=27425597 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27425597 #FOAvip English Wikipedia <ref>{{Cite pmid|27425597}}</ref> Individuals Hospitalized with Acute Mania Have Increased Exposure to Antimicrobial Medications #MMPMID27425597 Yolken R; Adamos M; Katsafanas E; Khushalani S; Origoni A; Savage C; Schweinfurth L; Stallings C; Sweeney K; Dickerson F Bipolar Disord 2016[Aug]; 18 (5): 404-9 PMID27425597show ga Objectives: We have preciously documented that many individuals with acute mania have immune activation. However the sources of immune activation have not been identified. We investigated whether individuals hospitalized with acute mania have evidence of bacterial infections as determined by the prescription of systemic antimicrobial agents. Methods: We assessed the recent prescription of systemic antimicrobial medications and the site of presumed bacterial infection in 234 individuals hospitalized for acute mania in either an inpatient unit or a day hospital. We also assessed individuals hospitalized for other psychiatric disorders (N=368) and controls (N=555). We employed logistic regression models to compare the rates of antibiotic prescription in individuals with the different diagnoses employing demographic variables as covariates. Results: We found that individuals hospitalized with acute mania had a substantially increased rate of recent antimicrobial prescription defined as exposure within 3 days of ascertainment (Adjusted Odds Ratio 5.5, 95% CI 2.2, 14.1, p<.0002). Overall a total of 18 of the 234 (7.7%)% of individuals hospitalized for acute mania were prescribed antibiotics as opposed to 7 of 555 (1.3%) controls. The prescription of antibiotics was associated with being in an inpatient unit as opposed to being in the day hospital and having increased mania symptom severity but not with other clinical ratings, demographic variables, or psychiatric medications. Hospitalization for other psychiatric disorders was not associated with the recent prescription of antimicrobial medications. The urinary tract was the most common site of infection in women while the respiratory tract and mucosal surfaces were the most common sites in men. Conclusion: Individuals hospitalized with acute mania have a markedly increased rate of bacterial infections as evidenced by the recent prescription of antimicrobial agents. The prevention and effective treatment of bacterial infections may be important interventions for the management of individuals with mania. äIndividuals Hospitalized with Acute Mania Have Increased Exposure to A(epmc).pdf DeepDyve Pubget Overpricing