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10.1016/j.yexcr.2017.05.004 http://scihub22266oqcxt.onion/10.1016/j.yexcr.2017.05.004 C5507591!5507591!28483447     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Exp+Cell+Res 2017 ; 356 (2): 160-5 Nephropedia Template TP {{tp|p=28483447|t=2017. Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies |pdf=|usr=}}{{28483447}} gab.com Text Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies JO: Exp Cell Res http://www.kidney.de/pget.php?&tw=1&pmid=28483447 #FOAvip The oxygen-sensitive hypoxia-inducible factor (HIF) pathway plays a central role in the control of erythropoiesis and iron metabolism. The discovery of prolyl hydroxylase domain (PHD) proteins as key regulators of HIF activity has led to the development of inhibitory compounds that are now in phase 3 clinical development for the treatment of renal anemia, a condition that is commonly found in patients with advanced chronic kidney disease. This review provides a concise overview of clinical effects associated with pharmacologic PHD inhibition and was written in memory of Professor Lorenz Poellinger. Twit Text FOAVip Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies ????Exp Cell Res http://www.kidney.de/pget.php?&tw=1&pmid=28483447 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28483447 #FOAvip English Wikipedia <ref>{{Cite pmid|28483447}}</ref> Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies #MMPMID28483447 Haase VH Exp Cell Res 2017[Jul]; 356 (2): 160-5 PMID28483447show ga The oxygen-sensitive hypoxia-inducible factor (HIF) pathway plays a central role in the control of erythropoiesis and iron metabolism. The discovery of prolyl hydroxylase domain (PHD) proteins as key regulators of HIF activity has led to the development of inhibitory compounds that are now in phase 3 clinical development for the treatment of renal anemia, a condition that is commonly found in patients with advanced chronic kidney disease. This review provides a concise overview of clinical effects associated with pharmacologic PHD inhibition and was written in memory of Professor Lorenz Poellinger. äTherapeutic targeting of the HIF oxygen-sensing pathway: Lessons learn(epmc).pdf DeepDyve Pubget Overpricing