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10.1038/nrm2178

http://scihub22266oqcxt.onion/10.1038/nrm2178
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C5507177!5507177!17473849
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suck abstract from ncbi


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pmid17473849      Nat+Rev+Mol+Cell+Biol 2007 ; 8 (6): 479-90
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  • RNA-binding proteins: modular design for efficient function #MMPMID17473849
  • Lunde BM; Moore C; Varani G
  • Nat Rev Mol Cell Biol 2007[Jun]; 8 (6): 479-90 PMID17473849show ga
  • Many RNA-binding proteins have modular structures, being composed of multiple repeats of just a few basic domains that are arranged in a variety of ways to satisfy their diverse functional requirements. Recent studies have investigated how different modules cooperate in regulating the RNA binding specificity and the biological activity of these proteins. They have also investigated how multiple modules cooperate with enzymatic domains to regulate the catalytic activity of enzymes acting upon RNA. These studies have shown how multiple modules define, for many RNA-binding proteins, the fundamental structural unit that is responsible for their biological function.
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