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10.1080/20013078.2017.1329476 http://scihub22266oqcxt.onion/10.1080/20013078.2017.1329476 C5505001!5505001!28717422     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Extracell+Vesicles 2017 ; 6 (1): ä Nephropedia Template TP {{tp|p=28717422|t=2017. Exosomes purified from a single cell type have diverse morphology |pdf=|usr=}}{{28717422}} gab.com Text Exosomes purified from a single cell type have diverse morphology JO: J Extracell Vesicles http://www.kidney.de/pget.php?&tw=1&pmid=28717422 #FOAvip Extracellular vesicles (EVs) are produced by all known organisms and are important for cell communication and physiology. Great morphological diversity has been described regarding EVs found in body fluids such as blood plasma, breast milk, and ejaculate. However, a detailed morphological analysis has never been performed on exosomes when purified from a single cell type.In this study we analysed and quantified, via multiple electron microscopy techniques, the morphology of exosomes purified from the human mast cell line HMC-1. The results revealed a wide diversity in exosome morphology, suggesting that subpopulations of exosomes with different and specific functions may exist. Our findings imply that a new, more efficient way of defining exosome subpopulations is necessary. A system was proposed where exosomes were classified into nine different categories according to their size and shape. Three additional morphological features were also found in exosomes regardless of their morphological classification.These findings show that exosomes purified from a single cell line are also morphologically diverse, similar to previous observations for EVs in body fluids. This knowledge can help to improve the interpretation of experimental results and widen our general understanding of the biological functions of exosomes. Twit Text FOAVip Exosomes purified from a single cell type have diverse morphology ????J Extracell Vesicles http://www.kidney.de/pget.php?&tw=1&pmid=28717422 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28717422 #FOAvip English Wikipedia <ref>{{Cite pmid|28717422}}</ref> Exosomes purified from a single cell type have diverse morphology #MMPMID28717422 Zabeo D; Cvjetkovic A; Lässer C; Schorb M; Lötvall J; Höög JL J Extracell Vesicles 2017[]; 6 (1): ä PMID28717422show ga Extracellular vesicles (EVs) are produced by all known organisms and are important for cell communication and physiology. Great morphological diversity has been described regarding EVs found in body fluids such as blood plasma, breast milk, and ejaculate. However, a detailed morphological analysis has never been performed on exosomes when purified from a single cell type.In this study we analysed and quantified, via multiple electron microscopy techniques, the morphology of exosomes purified from the human mast cell line HMC-1. The results revealed a wide diversity in exosome morphology, suggesting that subpopulations of exosomes with different and specific functions may exist. Our findings imply that a new, more efficient way of defining exosome subpopulations is necessary. A system was proposed where exosomes were classified into nine different categories according to their size and shape. Three additional morphological features were also found in exosomes regardless of their morphological classification.These findings show that exosomes purified from a single cell line are also morphologically diverse, similar to previous observations for EVs in body fluids. This knowledge can help to improve the interpretation of experimental results and widen our general understanding of the biological functions of exosomes. äExosomes purified from a single cell type have diverse morphology (epmc).pdf DeepDyve Pubget Overpricing