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10.5045/br.2017.52.2.84 http://scihub22266oqcxt.onion/10.5045/br.2017.52.2.84 C5503903!5503903!28698843     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Blood+Res 2017 ; 52 (2): 84-94 Nephropedia Template TP {{tp|p=28698843|t=2017. Diagnostic approaches for inherited hemolytic anemia in the genetic era |pdf=|usr=}}{{28698843}} gab.com Text Diagnostic approaches for inherited hemolytic anemia in the genetic era JO: Blood Res http://www.kidney.de/pget.php?&tw=1&pmid=28698843 #FOAvip Inherited hemolytic anemias (IHAs) are genetic diseases that present with anemia due to the increased destruction of circulating abnormal RBCs. The RBC abnormalities are classified into the three major disorders of membranopathies, hemoglobinopathies, and enzymopathies. Traditional diagnosis of IHA has been performed via a step-wise process combining clinical and laboratory findings. Nowadays, the etiology of IHA accounts for germline mutations of the responsible genes coding for the structural components of RBCs. Recent advances in molecular technologies, including next-generation sequencing, inspire us to apply these technologies as a first-line approach for the identification of potential mutations and to determine the novel causative genes in patients with IHAs. We herein review the concept and strategy for the genetic diagnosis of IHAs and provide an overview of the preparations for clinical applications of the new molecular technologies. Twit Text FOAVip Diagnostic approaches for inherited hemolytic anemia in the genetic era ????Blood Res http://www.kidney.de/pget.php?&tw=1&pmid=28698843 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28698843 #FOAvip English Wikipedia <ref>{{Cite pmid|28698843}}</ref> Diagnostic approaches for inherited hemolytic anemia in the genetic era #MMPMID28698843 Kim Y; Park J; Kim M Blood Res 2017[Jun]; 52 (2): 84-94 PMID28698843show ga Inherited hemolytic anemias (IHAs) are genetic diseases that present with anemia due to the increased destruction of circulating abnormal RBCs. The RBC abnormalities are classified into the three major disorders of membranopathies, hemoglobinopathies, and enzymopathies. Traditional diagnosis of IHA has been performed via a step-wise process combining clinical and laboratory findings. Nowadays, the etiology of IHA accounts for germline mutations of the responsible genes coding for the structural components of RBCs. Recent advances in molecular technologies, including next-generation sequencing, inspire us to apply these technologies as a first-line approach for the identification of potential mutations and to determine the novel causative genes in patients with IHAs. We herein review the concept and strategy for the genetic diagnosis of IHAs and provide an overview of the preparations for clinical applications of the new molecular technologies. äDiagnostic approaches for inherited hemolytic anemia in the genetic er(epmc).pdf DeepDyve Pubget Overpricing