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10.1038/nrn.2016.124 http://scihub22266oqcxt.onion/10.1038/nrn.2016.124 C5503467!5503467!27708356     free     free     free       Nat+Rev+Neurosci 2016 ; 17 (11): 681-91 Nephropedia Template TP {{tp|p=27708356|t=2016. Spatial Genome Organization and Cognition |pdf=|usr=}}{{27708356}} gab.com Text Spatial Genome Organization and Cognition JO: Nat Rev Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=27708356 #FOAvip Non-random chromosomal conformations, including promoter--enhancer loopings that bypass kilo- or megabases of linear genome, provide a critical layer of transcriptional regulation, and move vast amounts of non-coding sequence into the physical proximity of genes that are important for neurodevelopment, cognition and behavior. Activity-regulated changes of the neuronal ?3D genome? could govern transcriptional mechanisms associated with learning and plasticity, and loop-bound intergenic and intronic non-coding sequences have been implicated in psychiatric and adult-onset neurodegenerative disease. Recent studies have begun to clarify the roles of spatial genome organization in normal and abnormal cognition. Twit Text FOAVip Spatial Genome Organization and Cognition ????Nat Rev Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=27708356 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27708356 #FOAvip English Wikipedia <ref>{{Cite pmid|27708356}}</ref> Spatial Genome Organization and Cognition #MMPMID27708356 Rajarajan P; Gil SE; Brennand K; Akbarian S Nat Rev Neurosci 2016[Nov]; 17 (11): 681-91 PMID27708356show ga Non-random chromosomal conformations, including promoter--enhancer loopings that bypass kilo- or megabases of linear genome, provide a critical layer of transcriptional regulation, and move vast amounts of non-coding sequence into the physical proximity of genes that are important for neurodevelopment, cognition and behavior. Activity-regulated changes of the neuronal ?3D genome? could govern transcriptional mechanisms associated with learning and plasticity, and loop-bound intergenic and intronic non-coding sequences have been implicated in psychiatric and adult-onset neurodegenerative disease. Recent studies have begun to clarify the roles of spatial genome organization in normal and abnormal cognition. äSpatial Genome Organization and Cognition (epmc).pdf DeepDyve Pubget Overpricing