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10.1084/jem.20161070

http://scihub22266oqcxt.onion/10.1084/jem.20161070
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C5502424!5502424!28566277
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suck abstract from ncbi


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pmid28566277      J+Exp+Med 2017 ; 214 (7): 2121-38
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  • Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease #MMPMID28566277
  • Uderhardt S; Ackermann JA; Fillep T; Hammond VJ; Willeit J; Santer P; Mayr M; Biburger M; Miller M; Zellner KR; Stark K; Zarbock A; Rossaint J; Schubert I; Mielenz D; Dietel B; Raaz-Schrauder D; Ay C; Gremmel T; Thaler J; Heim C; Herrmann M; Collins PW; Schabbauer G; Mackman N; Voehringer D; Nadler JL; Lee JJ; Massberg S; Rauh M; Kiechl S; Schett G; O?Donnell VB; Krönke G
  • J Exp Med 2017[Jul]; 214 (7): 2121-38 PMID28566277show ga
  • Uderhardt et al. show that eosinophils accumulate in freshly formed thrombi, where they provide a procoagulant surface that is rich in oxidized phospholipids and allows assembly and activation of plasmatic coagulation factors. This mechanism stabilizes the thrombus and enables hemostasis but also contributes to thrombotic disease.
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