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10.5483/BMBRep.2017.50.6.039 http://scihub22266oqcxt.onion/10.5483/BMBRep.2017.50.6.039 C5498139!5498139!28270302     free     free     free       BMB+Rep 2017 ; 50 (6): 285-98 Nephropedia Template TP {{tp|p=28270302|t=2017. Cancer stem cell surface markers on normal stem cells |pdf=|usr=}}{{28270302}} gab.com Text Cancer stem cell surface markers on normal stem cells JO: BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=28270302 #FOAvip The cancer stem cell (CSC) hypothesis has captured the attention of many scientists. It is believed that elimination of CSCs could possibly eradicate the whole cancer. CSC surface markers provide molecular targeted therapies for various cancers, using therapeutic antibodies specific for the CSC surface markers. Various CSC surface markers have been identified and published. Interestingly, most of the markers used to identify CSCs are derived from surface markers present on human embryonic stem cells (hESCs) or adult stem cells. In this review, we classify the currently known 40 CSC surface markers into 3 different categories, in terms of their expression in hESCs, adult stem cells, and normal tissue cells. Approximately 73% of current CSC surface markers appear to be present on embryonic or adult stem cells, and they are rarely expressed on normal tissue cells. The remaining CSC surface markers are considerably expressed even in normal tissue cells, and some of them have been extensively validated as CSC surface markers by various research groups. We discuss the significance of the categorized CSC surface markers, and provide insight into why surface markers on hESCs are an attractive source to find novel surface markers on CSCs. Twit Text FOAVip Cancer stem cell surface markers on normal stem cells ????BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=28270302 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28270302 #FOAvip English Wikipedia <ref>{{Cite pmid|28270302}}</ref> Cancer stem cell surface markers on normal stem cells #MMPMID28270302 Kim WT; Ryu CJ BMB Rep 2017[Jun]; 50 (6): 285-98 PMID28270302show ga The cancer stem cell (CSC) hypothesis has captured the attention of many scientists. It is believed that elimination of CSCs could possibly eradicate the whole cancer. CSC surface markers provide molecular targeted therapies for various cancers, using therapeutic antibodies specific for the CSC surface markers. Various CSC surface markers have been identified and published. Interestingly, most of the markers used to identify CSCs are derived from surface markers present on human embryonic stem cells (hESCs) or adult stem cells. In this review, we classify the currently known 40 CSC surface markers into 3 different categories, in terms of their expression in hESCs, adult stem cells, and normal tissue cells. Approximately 73% of current CSC surface markers appear to be present on embryonic or adult stem cells, and they are rarely expressed on normal tissue cells. The remaining CSC surface markers are considerably expressed even in normal tissue cells, and some of them have been extensively validated as CSC surface markers by various research groups. We discuss the significance of the categorized CSC surface markers, and provide insight into why surface markers on hESCs are an attractive source to find novel surface markers on CSCs. äCancer stem cell surface markers on normal stem cells (epmc).pdf DeepDyve Pubget Overpricing